Evidence map›Paper›PMID 33917994›Full record

ArticleFoods (Basel, Switzerland)2021

Effect of Sea Buckthorn on Plasma Glucose in Individuals with Impaired Glucose Regulation: A Two-Stage Randomized Crossover Intervention Study.

Zhongxia Ren, Huiting Gong, Ai Zhao, Jian Zhang, Chenlu Yang, Peiyu Wang, Yumei Zhang

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Research progress of sea buckthorn (Frontiers in cardiovascular medicine · 2024
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhongxia RenDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China.ORCID 0000-0002-3424-5247
Huiting GongDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China.
Ai ZhaoVanke School of Public Health, Tsinghua University, Beijing 100091, China.
Jian ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China.ORCID 0000-0001-7246-2608
Chenlu YangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China.
Peiyu WangDepartment of Social Science and Health Education, School of Public Health, Peking University Health Science Center, Beijing 100191, China.
Yumei ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China.ORCID 0000-0002-0103-7900
Peking University · CNVanke (China) · CN

Funding

National Natural Science Foundation of China 81773420
6 · The paper itself

Abstract

Sea buckthorn (SB) has been indicated to have hypoglycemic potential, but its effects on glucose in people with impaired glucose regulation (IGR) are still unclear. This work presents a randomized, double-blinded, two-way crossover study. A total of 38 subjects with IGR completed the intervention of consuming sea buckthorn fruit puree (SBFP, 90 mL/day, five weeks), washing out (four weeks), and then consuming placebo (90 mL/day, five weeks) or in reverse order. In our methodology, a unified questionnaire was used to gather information on physical activity and dietary intakes, and physical examinations were performed to measure blood pressure, height, and weight. Fasting blood samples were collected to detect the fasting plasma glucose (FPG) and glycated serum protein (GSP). To calculate the area under the curve of 2 h postprandial plasma glucose (2 h PG-AUC), blood samples at t = 30, 60, and 120 min were also collected and analyzed. Effects of the intervention were evaluated by paired-sample Wilcoxon test and mixed model analyses. Our results show that the FPG in subjects with IGR decreased by a median reduction of 0.14 mmol/L after five weeks' consumption of SBFP, but increased by a median of 0.07 mmol/L after placebo intervention, and the comparison of these two interventions was statistically significant (

Indexed as

impaired glucose regulationplasma glucoserandomized crossover intervention studysea buckthorn

Identifiers

PMID33917994
PMCPMC8068387
OpenAlexW3195871193

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.