Evidence mapPaperPMID 33918317Full record

ReviewNutrients2021

Nutrition in Gynecological Diseases: Current Perspectives.

Michał Ciebiera, Sahar Esfandyari, Hiba Siblini, Lillian Prince, Hoda Elkafas, Cezary Wojtyła, Ayman Al-Hendy, Mohamed Ali

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Michał CiebieraSecond Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, 01-809 Warsaw, Poland.ORCID 0000-0001-5780-5983
Sahar EsfandyariDepartment of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA.
Hiba SibliniDepartment of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA.
Lillian PrinceBiological Sciences Division, Public Health Sciences, University of Chicago, Chicago, IL 60637, USA.
Hoda ElkafasDepartment of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-1058-3399
Cezary WojtyłaInternational Prevention Research Institute-Collaborating Centre, Calisia University, 62-800 Kalisz, Poland.ORCID 0000-0002-1249-1893
Ayman Al-HendyDepartment of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA.
Mohamed AliClinical Pharmacy Department, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.ORCID 0000-0002-9675-6691
University of Chicago · USUniversity of Illinois Chicago · USAin Shams University · EGChicago Department of Public Health · USPostgraduate School of Molecular Medicine · PL

Funding

Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroidsR01HD094378 · NICHD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Ayman Al-Hendy, THOMAS G BOYER · 2022 to 2022
$751k
NICHD NIH HHS R01 HD094378NIEHS NIH HHS R01 ES028615NIH HHS R01 HD094378-04, R01 ES 028615-02, R01 HD100367-01, U54 MD007602 and R01 HD094380-02.
6 · The paper itself

Abstract

Diet and nutrition are fundamental in maintaining the general health of populations, including women's health. Health status can be affected by nutrient deficiency and vice versa. Gene-nutrient interactions are important contributors to health management and disease prevention. Nutrition can alter gene expression, as well as the susceptibility to diseases, including cancer, through several mechanisms. Gynecological diseases in general are diseases involving the female reproductive system and include benign and malignant tumors, infections, and endocrine diseases. Benign diseases such as uterine fibroids and endometriosis are common, with a negative impact on women's quality of life, while malignant tumors are among the most common cause of death in the recent years. In this comprehensive review article, a bibliographic search was performed for retrieving information about nutrients and how their deficiencies can be associated with gynecological diseases, namely polycystic ovary syndrome, infertility, uterine fibroids, endometriosis, dysmenorrhea, and infections, as well as cervical, endometrial, and ovarian cancers. Moreover, we discussed the potential beneficial impact of promising natural compounds and dietary supplements on alleviating these significant diseases.

Indexed as

Deficiency DiseasesFemaleGenital Diseases, FemaleHumansNutritional StatusNutrition Therapycervical cancercomplementary and alternative medicinedietdysmenorrheaendometrial cancerendometriosisgynecological diseasesinfectioninfertilitymicrobiomenutrientsnutritionovarian cancerPCOSuterine fibroids

Identifiers

PMID33918317
PMCPMC8065992
OpenAlexW3142567567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.