Evidence map›Paper›PMID 33918360›Full record

ReviewNutrients2021

Adiponectin: Structure, Physiological Functions, Role in Diseases, and Effects of Nutrition.

Kayvan Khoramipour, Karim Chamari, Amirhosein Ahmadi Hekmatikar, Amirhosein Ziyaiyan, Shima Taherkhani, Nihal M Elguindy, Nicola Luigi Bragazzi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 9 pooled it
29.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

178 citing papers in PubMed, 9 syntheses or guidelines pooled it, 306 citations in OpenAlex.

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118 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Kayvan KhoramipourDepartment of Physiology and Pharmacology, Afzalipour Medical Faculty, Physiology Research Center and Neuroscience Research Center, Kerman University of Medical Sciences, Kerman 7616913555, Iran.ORCID 0000-0003-1598-8640
Karim ChamariASPETAR, Qatar Orthopaedic and Sports Medicine Hospital, Doha 29222, Qatar.
Amirhosein Ahmadi HekmatikarPhysical Education & Sport Sciences Department, Faculty of Humanities, Tarbiat Modares University, Tehran 1411713116, Iran.
Amirhosein ZiyaiyanDepartment of Exercise Physiology, Faculty of Physical Education and Sports Science, University of Tehran, Tehran 1439956141, Iran.
Shima TaherkhaniDepartment of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht 4199843653, Iran.ORCID 0000-0002-9088-9047
Nihal M ElguindyBiochemistry Department, Faculty of Science, Alexandria University, Alexandria 21568, Egypt.
Nicola Luigi BragazziLaboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON M3J 1P3, Canada.ORCID 0000-0001-8409-868X
Alexandria University · EGKerman University of Medical Sciences · IRQatar Orthopaedic and Sports Medicine Hospital · QATarbiat Modares University · IRUniversity of Guilan · IRUniversity of Tehran · IRYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available evidence suggests that adiponectin is involved in a variety of physiological functions, molecular and cellular events, including lipid metabolism, energy regulation, immune response and inflammation, and insulin sensitivity. It has a protective effect on neurons and neural stem cells. Adiponectin levels have been reported to be negatively correlated with cancer, cardiovascular disease, and diabetes, and shown to be affected (i.e., significantly increased) by proper healthy nutrition. The present review comprehensively overviews the role of adiponectin in a range of diseases, showing that it can be used as a biomarker for diagnosing these disorders as well as a target for monitoring the effectiveness of preventive and treatment interventions.

Indexed as

AdiponectinAdipose TissueAlzheimer DiseaseAnimalsBiomarkersCardiovascular DiseasesDiabetes MellitusEnergy MetabolismHumansImmunityInflammationInsulin ResistanceLipid MetabolismNeoplasmsNutritional StatusProtective FactorsAdiponectinBiomarkersadipokineadiponectinadipose tissuesbiomarkercancerdiseasenutrition

Identifiers

PMID33918360
PMCPMC8066826
OpenAlexW3144213171

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.