Evidence map›Paper›PMID 33919619›Full record

ArticleCancers2021

The New Serum-Free OptiPASS

Antoine Goisnard, Clémence Dubois, Pierre Daumar, Corinne Aubel, Marie Depresle, Jean Gauthier, Bernard Vidalinc, Frédérique Penault-Llorca, Emmanuelle Mounetou, Mahchid Bamdad

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. LightSpotCancers · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antoine GoisnardImagerie Moléculaire et Stratégies Théranostiques, Institut Universitaire de Technologie, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.
Clémence DuboisImagerie Moléculaire et Stratégies Théranostiques, Institut Universitaire de Technologie, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.
Pierre DaumarImagerie Moléculaire et Stratégies Théranostiques, Institut Universitaire de Technologie, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.ORCID 0000-0003-0386-7171
Corinne AubelImagerie Moléculaire et Stratégies Théranostiques, Faculté de Médecine, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.ORCID 0000-0003-4500-6505
Marie DepresleBIOMARQUEURS Company, 5 Avenue Blaise Pascal, 63178 Aubière, France.
Jean GauthierBIOMARQUEURS Company, 5 Avenue Blaise Pascal, 63178 Aubière, France.
Bernard VidalincBIOMARQUEURS Company, 5 Avenue Blaise Pascal, 63178 Aubière, France.
Frédérique Penault-LlorcaImagerie Moléculaire et Stratégies Théranostiques, Centre de Lutte Contre le Cancer Jean Perrin, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.
Emmanuelle MounetouImagerie Moléculaire et Stratégies Théranostiques, Institut Universitaire de Technologie, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.
Mahchid BamdadImagerie Moléculaire et Stratégies Théranostiques, Institut Universitaire de Technologie, Université Clermont Auvergne, UMR INSERM-UCA, U1240, 63000 Clermont Ferrand, France.ORCID 0000-0002-2474-6910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer spheroids are very effective preclinical models to improve anticancer drug screening. In order to optimize and extend the use of spheroid models, these works were focused on the development of a new storage concept to maintain these models in the longer term using the Triple-Negative Breast Cancer MDA-MB-231 spheroid models. The results highlight that the combination of a temperature of 4 °C and oxygen-free conditions allowed the spheroid characteristics of OptiPASS

Indexed as

drug screeningMDA-MB-231 spheroidsnew spheroid storage conceptpreclinical spheroid modelstriple-negative breast cancer

Identifiers

PMID33919619
PMCPMC8073891

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.