Evidence map›Paper›PMID 33919740›Full record

ArticleBrain sciences2021

Recalled Parental Bonding Interacts with Oxytocin Receptor Gene Polymorphism in Modulating Anxiety and Avoidance in Adult Relationships.

Ilaria Cataldo, Andrea Bonassi, Bruno Lepri, Jia Nee Foo, Peipei Setoh, Gianluca Esposito

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ilaria CataldoDepartment of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, Italy.ORCID 0000-0002-3969-4455
Andrea BonassiDepartment of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, Italy.ORCID 0000-0003-2532-3423
Bruno LepriMobile and Social Computing Lab, Bruno Kessler Foundation, 38123 Trento, Italy.ORCID 0000-0003-1275-2333
Jia Nee FooHuman Genetics, Genome Institute of Singapore, Singapore 138672, Singapore.ORCID 0000-0001-9899-2308
Peipei SetohPsychology Program, School of Social Sciences, Nanyang Technological University, Singapore 639818, Singapore.ORCID 0000-0002-7830-5977
Gianluca EspositoDepartment of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, Italy.ORCID 0000-0002-9442-0254
Nanyang Technological University · SGUniversity of Trento · ITFondazione Bruno Kessler · IT

Funding

Ministry of Education - Singapore ACR Tier-1Ministry of Education - Singapore Social Science Research Thematic Grant MOE2016-SSRTG-017Nanyang Technological University NAP Start-up Grant M4081597
6 · The paper itself

Abstract

Early interactions with significant individuals affect social experience throughout the course of a lifetime, as a repeated and prolonged perception of different levels of care, independence, or control influences the modulation of emotional regulatory processes. As many factors play a role in shaping the expectations and features of social interaction, in this study, we considered the influence of parental bonding and genetic allelic variation of oxytocin receptor gene polymorphism (rs53576) over levels of experienced anxiety and avoidance in 313 young adults belonging to two different cultural contexts, namely Italy and Singapore. Results highlighted a major effect of maternal characteristics, care, and overprotection, with differences between the two cultural groups. Additionally, the interaction between rs53576 and maternal overprotection suggested different environmental susceptibility in the Italian sample and the Singaporean one. Implications for clinical work and future steps are described in the Conclusion.

Indexed as

close relationshipcross-cultural studyethnicitygene-culture interactiongene-environment interactionoxytocin receptor geneparental bondingrs53576social behaviorsocial development

Identifiers

PMID33919740
PMCPMC8070703
OpenAlexW3155737126

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.