Evidence map›Paper›PMID 33920984›Full record

ArticleBiology2021

Salvage Boron Neutron Capture Therapy for Malignant Brain Tumor Patients in Compliance with Emergency and Compassionate Use: Evaluation of 34 Cases in Taiwan.

Yi-Wei Chen, Yi-Yen Lee, Chun-Fu Lin, Po-Shen Pan, Jen-Kun Chen, Chun-Wei Wang, Shih-Ming Hsu, Yu-Cheng Kuo, Tien-Li Lan, Sanford P C Hsu and 25 more

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 14 institutions in 3 countries.

Yi-Wei ChenFaculty of Medicine, National Yang Ming Chiao Tung University, Taipei City 112304, Taiwan.
Yi-Yen LeeFaculty of Medicine, National Yang Ming Chiao Tung University, Taipei City 112304, Taiwan.ORCID 0000-0003-3709-885X
Chun-Fu LinDepartment of Neurosurgery, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Po-Shen PanDepartment of Chemistry, Tamkang University, New Taipei City 251301, Taiwan.
Jen-Kun ChenInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli County 350401, Taiwan.ORCID 0000-0002-3433-5971
Chun-Wei WangDepartment of Oncology, National Taiwan University Hospital, Taipei City 100229, Taiwan.
Shih-Ming HsuDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei City 112304, Taiwan.
Yu-Cheng KuoDepartment of Radiotherapy, China Medical University Hospital, Taichung City 404327, Taiwan.
Tien-Li LanDepartment of Oncology, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Sanford P C HsuDepartment of Neurosurgery, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Muh-Lii LiangDepartment of Neurosurgery, Mackay Memorial Hospital, Taipei City 104217, Taiwan.ORCID 0000-0002-5923-9812
Robert Hsin-Hung ChenDepartment of Neurosurgery, Mackay Memorial Hospital, Taipei City 104217, Taiwan.
Feng-Chi ChangDepartment of Radiology, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Chih-Chun WuDepartment of Radiology, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Shih-Chieh LinDepartment of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Hsiang-Kuang LiangDepartment of Oncology, National Taiwan University Hospital, Taipei City 100229, Taiwan.
Jia-Cheng LeeDepartment of Oncology, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Shih-Kuan ChenDepartment of Oncology, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.ORCID 0000-0001-8174-8077
Hong-Ming LiuNuclear Science & Technology Development Department, National Tsing-Hua University, Hsinchu City 30013, Taiwan.ORCID 0000-0001-9989-9746
Jinn-Jer PeirNuclear Science & Technology Development Department, National Tsing-Hua University, Hsinchu City 30013, Taiwan.ORCID 0000-0002-9196-4897
Ko-Han LinDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Wen-Sheng HuangDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Kuan-Hsuan ChenDepartment of Pharmacy, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Yu-Mei KangFaculty of Medicine, National Yang Ming Chiao Tung University, Taipei City 112304, Taiwan.
Shueh-Chun LiouFaculty of Medicine, National Yang Ming Chiao Tung University, Taipei City 112304, Taiwan.
Chun-Chieh WangDepartment of Radiation Oncology, Chang-Gung Memorial Hospital, Linkou Dist, New Taipei City 333011, Taiwan.
Ping-Ching PaiDepartment of Radiation Oncology, Chang-Gung Memorial Hospital, Linkou Dist, New Taipei City 333011, Taiwan.
Chih-Wei LiDelicate Clinic, Taishan Dist, New Taipei City 243081, Taiwan.ORCID 0000-0003-4052-3511
Daniel Quah Song ChiekDivision of Radiation Oncology, National Cancer Centre, Singapore 169610, Singapore.
Tai-Tong WongDepartment of Neurosurgery, Taipei Medical University Hospital, Taipei City 110301, Taiwan.ORCID 0000-0003-4075-6227
Shih-Hwa ChiouDepartment of Medical Research, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.
Yee ChaoDepartment of Oncology, Taipei Veterans General Hospital, Taipei City 11217, Taiwan.ORCID 0000-0001-5578-340X
Hiroki TanakaInstitute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka Prefecture 590-0494, Japan.
Fong-In ChouNuclear Science & Technology Development Department, National Tsing-Hua University, Hsinchu City 30013, Taiwan.
Koji OnoKansai BNCT Medical Center, Osaka Medical College, Takatsuki City, Osaka Prefecture 569-8686, Japan.
Taipei Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TWChang Gung Memorial Hospital · TWNational Tsing Hua University · TWMackay Memorial Hospital · TWChina Medical University · TWChung Shan Hospital · TWKyoto University · JPNational Cancer Centre Singapore · SGNational Health Research Institutes · TWNational Taiwan University Hospital · TWOsaka Medical and Pharmaceutical University · JPTaipei Medical University Hospital · TWTamkang University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although boron neutron capture therapy (BNCT) is a promising treatment option for malignant brain tumors, the optimal BNCT parameters for patients with immediately life-threatening, end-stage brain tumors remain unclear. We performed BNCT on 34 patients with life-threatening, end-stage brain tumors and analyzed the relationship between survival outcomes and BNCT parameters. Before BNCT, MRI and

Indexed as

BNCTglioblastomaradioresistanceT/B ratioT/N ratio

Identifiers

PMID33920984
PMCPMC8071294
OpenAlexW3155035903

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.