Evidence map›Paper›PMID 33922341›Full record

SynthesisNutrients2021

Crosstalk of Magnesium and Serum Lipids in Dyslipidemia and Associated Disorders: A Systematic Review.

Mihnea-Alexandru Găman, Elena-Codruța Dobrică, Matei-Alexandru Cozma, Ninel-Iacobus Antonie, Ana Maria Alexandra Stănescu, Amelia Maria Găman, Camelia Cristina Diaconu

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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  18. Biomolecules · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mihnea-Alexandru GămanFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-7133-8875
Elena-Codruța DobricăDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Matei-Alexandru CozmaDepartment of Gastroenterology, Colentina Clinical Hospital, 20125 Bucharest, Romania.ORCID 0000-0002-4998-0105
Ninel-Iacobus AntonieDepartment of Internal Medicine, Clinical Emergency Hospital of Bucharest, 14461 Bucharest, Romania.
Ana Maria Alexandra StănescuFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-4807-9470
Amelia Maria GămanDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0001-6974-2772
Camelia Cristina DiaconuFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-6837-260X
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROSpitalul Clinic Colentina · ROUniversity of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyslipidemia is a significant threat to public health worldwide and the identification of its pathogenic mechanisms, as well as novel lipid-lowering agents, are warranted. Magnesium (Mg) is a key element to human health and its deficiency has been linked to the development of lipid abnormalities and related disorders, such as the metabolic syndrome, type 2 diabetes mellitus, or cardiovascular disease. In this review, we explored the associations of Mg (dietary intake, Mg concentrations in the body) and the lipid profile, as well as the impact of Mg supplementation on serum lipids. A systematic search was computed in PubMed/MEDLINE and the Cochrane Library and 3649 potentially relevant papers were detected and screened (n = 3364 following the removal of duplicates). After the removal of irrelevant manuscripts based on the screening of their titles and abstracts (n = 3037), we examined the full-texts of 327 original papers. Finally, after we applied the exclusion and inclusion criteria, a number of 124 original articles were included in this review. Overall, the data analyzed in this review point out an association of Mg concentrations in the body with serum lipids in dyslipidemia and related disorders. However, further research is warranted to clarify whether a higher intake of Mg from the diet or via supplements can influence the lipid profile and exert lipid-lowering actions.

Indexed as

DyslipidemiasHealth StatusHumansLipidsMagnesiumRandomized Controlled Trials as TopicLipidsMagnesiumcholesteroldiabetesdyslipidemiahyperlipidemiahypomagnesemialipidsmagnesemiamagnesiummetabolic syndrometriglycerides

Identifiers

PMID33922341
PMCPMC8146023
OpenAlexW3154578606

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.