Evidence map›Paper›PMID 33924284›Full record

ArticlePharmaceutics2021

Cationic Single-Chained Surfactants with a Functional Group at the End of the Hydrophobic Tail DNA Compacting Efficiency.

José Antonio Lebrón, Pilar López-Cornejo, Elena García-Dionisio, Pablo Huertas, Margarita García-Calderón, María Luisa Moyá, Francisco José Ostos, Manuel López-López

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

José Antonio LebrónDepartamento de Química Física, Facultad de Química, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.ORCID 0000-0002-6938-3690
Pilar López-CornejoDepartamento de Química Física, Facultad de Química, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.ORCID 0000-0002-5825-9483
Elena García-DionisioDepartamento de Química Física, Facultad de Química, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.
Pablo HuertasDepartamento de Genética, Universidad de Sevilla y Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, 41092 Sevilla, Spain.ORCID 0000-0002-1756-4449
Margarita García-CalderónDepartamento de Bioquímica Vegetal y Biología Molecular, Facultad de Química, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.
María Luisa MoyáDepartamento de Química Física, Facultad de Química, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.ORCID 0000-0002-2736-9348
Francisco José OstosDepartamento de Química Física, Facultad de Química, Universidad de Sevilla, C/Profesor García González 1, 41012 Sevilla, Spain.ORCID 0000-0001-6583-6974
Manuel López-LópezDepartamento de Ingeniería Química, Química Física y Ciencias de Materiales, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus de El Carmen, Avenida de las Fuerzas Armadas s/n, 21071 Huelva, Spain.ORCID 0000-0001-9060-9554
Universidad de Sevilla · ESCentro Andaluz de Biología Molecular y Medicina Regenerativa · ESUniversidad de Huelva · ES

Funding

Consejería de Educación y Ciencia de la Junta de Andalucía FQM-206Consejería de Educación y Ciencia de la Junta de Andalucía FQM-274Consejería de Educación y Ciencia de la Junta de Andalucía PI-0005-2018European Union (FEDER Funds) FEDER FundsVI Plan Propio Universidad de Sevilla PP2019/00000748
6 · The paper itself

Abstract

The interaction between calf-thymus DNA, ctDNA, and various single-chained surfactants with different functional groups at the end of hydrophobic tail was studied with the goal of investigating the influence of the functional group nature on surfactant DNA compacting efficiency. The surfactants investigated were dodecyltriethylammonium bromide (DTEABr), triethyl(1-phenoxydodecyl)ammonium bromide (12PhBr), triethyl(2-naphthoxydodecyl)ammonium bromide (12NBr) and 11-(isonicotinoyloxy)-

Indexed as

cationic surfactantsDNA compacting efficiencygene transfectionlipoplexesliposomes

Identifiers

PMID33924284
PMCPMC8074900
OpenAlexW3154057575

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.