Evidence mapPaperPMID 33925539Full record

ReviewInternational journal of molecular sciences2021

DNA Methylation of the Angiotensinogen Gene,

Yoshimichi Takeda, Masashi Demura, Takashi Yoneda, Yoshiyu Takeda

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Nrf2Frontiers in genetics · 2023
    Article
  14. Review
  15. Review
  16. Article
  17. Aldosterone breakthrough from a pharmacological perspective.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yoshimichi TakedaDepartment of Endocrinology and Metabolism, Kanazawa University Hospital, Kanazawa 920-8641, Japan.
Masashi DemuraDepartment of Hygiene, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.
Takashi YonedaInstitute of Liberal Arts and Science, Kanazawa University, Kanazawa 920-8641, Japan.ORCID 0000-0002-0921-158X
Yoshiyu TakedaDepartment of Endocrinology and Metabolism, Kanazawa University Hospital, Kanazawa 920-8641, Japan.
Kanazawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensinogen (AGT) and aldosterone play key roles in the regulation of blood pressure and are implicated in the pathogenesis of cardiovascular diseases. DNA methylation typically acts to repress gene transcription. The aldosterone synthase gene

Indexed as

AldosteroneAngiotensin IIAngiotensinogenCardiovascular DiseasesCCAAT-Enhancer-Binding ProteinsCytochrome P-450 CYP11B2DNA MethylationEpigenesis, GeneticGene ExpressionGene Expression RegulationHumansHypertensionPromoter Regions, GeneticTranscription FactorsAldosteroneAngiotensin IIAngiotensinogenCCAAT-Enhancer-Binding ProteinsCytochrome P-450 CYP11B2Transcription Factorsaldosteroneangiotensinogencardiovascular diseasemethylationsalt

Identifiers

PMID33925539
PMCPMC8123855
OpenAlexW3159916403

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.