Evidence map›Paper›PMID 33926125›Full record

ArticleInternational journal of molecular sciences2021

Cellular Response to Individual Components of the Platelet Concentrate.

Vera Sovkova, Karolina Vocetkova, Věra Hedvičáková, Veronika Hefka Blahnová, Matěj Buzgo, Evzen Amler, Eva Filová

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Platelet Derivatives and the Immunomodulation of Wound Healing.International journal of molecular sciences · 2022
    Review
  4. Molecular Research on Platelet Activity in Health and Disease 3.0.International journal of molecular sciences · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vera SovkovaDepartment of Biophysics, 2nd Faculty of Medicine, Charles University, V Uvalu 84, 150 06 Prague, Czech Republic.ORCID 0000-0002-4618-9828
Karolina VocetkovaDepartment of Tissue Engineering, Institute of Experimental Medicine, The Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.ORCID 0000-0002-5664-0109
Věra HedvičákováDepartment of Tissue Engineering, Institute of Experimental Medicine, The Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Veronika Hefka BlahnováDepartment of Biophysics, 2nd Faculty of Medicine, Charles University, V Uvalu 84, 150 06 Prague, Czech Republic.
Matěj BuzgoUniversity Centre for Energy Efficient Buildings, Czech Technical University in Prague, Trinecka 1024, 273 43 Bustehrad, Czech Republic.
Evzen AmlerDepartment of Biophysics, 2nd Faculty of Medicine, Charles University, V Uvalu 84, 150 06 Prague, Czech Republic.
Eva FilováDepartment of Tissue Engineering, Institute of Experimental Medicine, The Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.ORCID 0000-0003-1028-605X
Czech Academy of Sciences · CZCharles University · CZCzech Technical University in Prague · CZ

Funding

EU Horizon 2020 MSCA-RISE-2018 - Research and Innovation Staff Exchange programme project IP Osteo "Induced pluripotent stem cell for bone and cartilage defects" under grant agreement 824007Internal Grant Agency of the Ministry of Health of the Czech Republic No 17-32285AMinistry of Education, Youth and Sports of the Czech Republic within the National Sustainabili-ty Programme I: projects No. LO1508, Operational Program - Prague Competitiveness CZ.2.16/3.1.00/21528
6 · The paper itself

Abstract

Platelet concentrates and especially their further product platelet lysate, are widely used as a replacement for cell culturing. Platelets contain a broad spectrum of growth factors and bioactive molecules that affect cellular fate. However, the cellular response to individual components of the human platelet concentrate is still unclear. The aim of this study was to observe cellular behavior according to the individual components of platelet concentrates. The bioactive molecule content was determined. The cells were supplemented with a medium containing 8% (

Indexed as

AlbuminsBecaplerminBlood PlateletsCell Culture TechniquesCell ProliferationChemokinesCulture MediaFibrinogenFibroblast Growth Factor 7FibroblastsHepatocyte Growth FactorHumansInsulin-Like Growth Factor IMesenchymal Stem CellsPlasmaPlatelet-Rich PlasmaAlbuminsBecaplerminChemokinesCulture MediaFibrinogenFibroblast Growth Factor 7Hepatocyte Growth FactorInsulin-Like Growth Factor IProto-Oncogene Proteins c-sisfibroblastsmesenchymal stem cellsplasmaplatelets

Identifiers

PMID33926125
PMCPMC8123700
OpenAlexW3157585399

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.