Evidence map›Paper›PMID 33927775›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2021

The Protective Effect of Traditional Chinese Medicine on Liver Ischemia-Reperfusion Injury.

Wen Ma, Songling Tang, Dina Xie, Guoqiang Gu, Lu Gan

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. International journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen MaSichuan University-The Hong Kong Polytechnic University Institute for Disaster Management and Reconstruction, Chengdu 610207, China.ORCID https://orcid.org/0000-0002-5896-019X
Songling TangResearch Laboratory of Emergency Medicine, Department of Emergency Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0002-3979-4261
Dina XieDepartment of Emergency Medicine and Medicine, Thomas Jefferson University, Philadelphia 19107, PA, USA.
Guoqiang GuCardiology Department, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China.ORCID https://orcid.org/0000-0002-7186-3036
Lu GanResearch Laboratory of Emergency Medicine, Department of Emergency Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0001-8665-2760

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver ischemia-reperfusion (I/R) injury occurs during transplantation and major hepatic surgery, which may lead to postoperative liver dysfunction. More and more traditional Chinese medicines (TCMs) have been used to treat liver ischemia-reperfusion injury. The purpose of this review is to evaluate the different protective effects of TCMs in the treatment of liver ischemia-reperfusion injury and to summarize its possible mechanisms. The results indicate that TCMs attenuate liver I/R injury via multiple mechanisms, including antioxidation stress, anti-inflammatory response, antiapoptosis, and inhibiting endoplasmic reticulum stress. However, the in-depth mechanism of the protective effects of these traditional Chinese medicines still remains unknown.

Identifiers

PMID33927775
PMCPMC8049787

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.