Evidence map›Paper›PMID 33928091›Full record

ReviewFrontiers in cell and developmental biology2021

Phospho-Regulation of Meiotic Prophase.

Funda M Kar, Andreas Hochwagen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Editorial: Molecular architecture and dynamics of meiotic chromosomes.Frontiers in cell and developmental biology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Cyclins and CDKs in the regulation of meiosis-specific events.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Funda M KarDepartment of Biology, New York University, New York, NY, United States.
Andreas HochwagenDepartment of Biology, New York University, New York, NY, United States.
New York University · US

Funding

Mechanisms of Chromosome Scale Signal PropagationR01GM111715 · NIGMS · NEW YORK UNIVERSITY · PI HOCHWAGEN, ANDREAS · 2015 to 2022
$2.6M
Chromosomal control of meiotic double-strand break formationR01GM123035 · NIGMS · NEW YORK UNIVERSITY · PI HOCHWAGEN, ANDREAS · 2018 to 2021
$1.2M
NIGMS NIH HHS R01 GM111715NIGMS NIH HHS R01 GM123035
6 · The paper itself

Abstract

Germ cells undergoing meiosis rely on an intricate network of surveillance mechanisms that govern the production of euploid gametes for successful sexual reproduction. These surveillance mechanisms are particularly crucial during meiotic prophase, when cells execute a highly orchestrated program of chromosome morphogenesis and recombination, which must be integrated with the meiotic cell division machinery to ensure the safe execution of meiosis. Dynamic protein phosphorylation, controlled by kinases and phosphatases, has emerged as one of the main signaling routes for providing readout and regulation of chromosomal and cellular behavior throughout meiotic prophase. In this review, we discuss common principles and provide detailed examples of how these phosphorylation events are employed to ensure faithful passage of chromosomes from one generation to the next.

Indexed as

checkpointkinasemeiosisphosphataseprophaserecombinationsynapsis

Identifiers

PMID33928091
PMCPMC8076904
OpenAlexW3154627194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.