Evidence map›Paper›PMID 33928434›Full record

ReviewJournal of molecular medicine (Berlin, Germany)2021

The mutual interplay of redox signaling and connexins.

Kai Zhang, Qi-Wen Guan, Xin-Yu Zhou, Qin-Xuan Xia, Xi-Xi Yin, Hong-Hao Zhou, Xiao-Yuan Mao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular medicine (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Fundamentals of redox regulation in biology.Nature reviews. Molecular cell biology · 2024
    Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kai Zhang *Department of Clinical Pharmacology, Xiangya Hospital and Institute of Clinical Pharmacology, Central South University, 87 Xiangya Road, Changsha, 410008, People's Republic of China.
Qi-Wen Guan *Department of Clinical Pharmacology, Xiangya Hospital and Institute of Clinical Pharmacology, Central South University, 87 Xiangya Road, Changsha, 410008, People's Republic of China.
Xin-Yu Zhou *Department of Neurology, Lianyungang Hospital affiliated with Xuzhou Medical College, Tongguan Road, 182, Lianyungang, Jiangsu, People's Republic of China.
Qin-Xuan XiaDepartment of Clinical Pharmacology, Xiangya Hospital and Institute of Clinical Pharmacology, Central South University, 87 Xiangya Road, Changsha, 410008, People's Republic of China.
Xi-Xi YinDepartment of Pediatrics, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, People's Republic of China.
Hong-Hao ZhouDepartment of Clinical Pharmacology, Xiangya Hospital and Institute of Clinical Pharmacology, Central South University, 87 Xiangya Road, Changsha, 410008, People's Republic of China.
Xiao-Yuan MaoDepartment of Clinical Pharmacology, Xiangya Hospital and Institute of Clinical Pharmacology, Central South University, 87 Xiangya Road, Changsha, 410008, People's Republic of China. xiaoyuanm@csu.edu.cn.ORCID http://orcid.org/0000-0002-5149-1204
Central South University · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Connexins (Cxs) are ubiquitous transmembrane proteins that possess both channel function (e.g., formations of gap junction and hemichannel) and non-channel properties (e.g., gene transcription and protein-protein interaction). Several factors have been identified to play a role in the regulation of Cxs, which include those acting intracellularly, as redox potential, pH, intramolecular interactions, and post-translational modifications (e.g., phosphorylation, S-nitrosylation) as well as those acting extracellularly, such as Ca

Indexed as

AnimalsConnexinsHumansOxidation-ReductionSignal TransductionConnexinsConnexinDisease pathologyMutual interplayRedoxTherapy

Identifiers

PMID33928434
OpenAlexW3159204136

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.