Evidence map›Paper›PMID 33929568›Full record

ArticleBrain structure & function2021

A fully segmented 3D anatomical atlas of a lizard brain.

Daniel Hoops, Hanyi Weng, Ayesha Shahid, Philip Skorzewski, Andrew L Janke, Jason P Lerch, John G Sled

Abstract read
PubMed Publisher
In one paragraph

Article in Brain structure & function, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Daniel HoopsMouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada. daniel.hoops@mail.mcgill.ca.ORCID http://orcid.org/0000-0002-5707-3513
Hanyi WengMouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada.
Ayesha ShahidMouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada.
Philip SkorzewskiMouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada.
Andrew L JankeCenter for Advanced Imaging, The University of Queensland, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0003-0547-5171
Jason P LerchMouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0001-6164-2881
John G SledMouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-4461-283X
Hospital for Sick Children · CAUniversity of Toronto · CAThe University of Queensland · AU

Funding

Natural Sciences and Engineering Research Council of Canada PDF5171462018
6 · The paper itself

Abstract

As the relevance of lizards in evolutionary neuroscience increases, so does the need for more accurate anatomical references. Moreover, the use of magnetic resonance imaging (MRI) in evolutionary neuroscience is becoming more widespread; this represents a fundamental methodological shift that opens new avenues of investigative possibility but also poses new challenges. Here, we aim to facilitate this shift by providing a three-dimensional segmentation atlas of the tawny dragon brain. The tawny dragon (Ctenophorus decresii) is an Australian lizard of increasing importance as a model system in ecology and, as a member of the agamid lizards, in evolution. Based on a consensus average 3D image generated from the MRIs of 13 male tawny dragon heads, we identify and segment 224 structures visible across the entire lizard brain. We describe the relevance of this atlas to the field of evolutionary neuroscience and propose further experiments for which this atlas can provide the foundation. This advance in defining lizard neuroanatomy will facilitate numerous studies in evolutionary neuroscience. The atlas is available for download as a supplementary material to this manuscript and through the Open Science Framework (OSF; https://doi.org/10.17605/OSF.IO/UJENQ ).

Indexed as

BrainLizardsAnimalsAustraliaImaging, Three-DimensionalMagnetic Resonance ImagingMaleAgamidEvolutionary neuroscienceMagnetic resonance imagingRegistrationReptileSegmentation

Identifiers

PMID33929568
OpenAlexW3158914306

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.