Evidence mapPaperPMID 33934103Full record

ArticleTranslational psychiatry2021

Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery.

Henry K Karlsson, Lauri Tuominen, Semi Helin, Paulina Salminen, Pirjo Nuutila, Lauri Nummenmaa

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. The role of the gut-brain axis in bariatric surgery.Current opinion in neurobiology · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Henry K KarlssonTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland. hekrka@utu.fi.ORCID 0000-0001-6734-7891
Lauri TuominenTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0002-8726-0467
Semi HelinTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.
Paulina SalminenDepartment of Surgery, University of Turku, Turku, Finland.ORCID 0000-0001-6435-9264
Pirjo NuutilaTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.
Lauri NummenmaaTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0002-2497-9757
University of Turku · FIUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a growing burden to health and the economy worldwide. Obesity is associated with central µ-opioid receptor (MOR) downregulation and disruption of the interaction between MOR and dopamine D

Indexed as

Bariatric SurgeryObesity, MorbidAnalgesics, OpioidDopamineFemaleHumansPositron-Emission TomographyReceptors, Dopamine D2Weight LossAnalgesics, OpioidDopamineReceptors, Dopamine D2

Identifiers

PMID33934103
PMCPMC8088437
OpenAlexW3112661380

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.