Evidence map›Paper›PMID 33934396›Full record

ArticleMagnetic resonance in medicine2021

Magnetic resonance angiography and perfusion mapping by arterial spin labeling using Fourier transform-based velocity-selective pulse trains: Examination on a commercial perfusion phantom.

Feng Xu, Dan Zhu, Hongli Fan, Hanzhang Lu, Dapeng Liu, Wenbo Li, Qin Qin

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng XuThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-7958-3787
Dan ZhuThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-0940-1519
Hongli FanThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.
Hanzhang LuThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.
Dapeng LiuThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-4432-3202
Wenbo LiThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-0199-1534
Qin QinThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-6432-2944

Funding

TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI PEKAR, JAMES J. · 2012 to 2020
$13.1M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
Diversity Suppplement (CIRCADIAN) Circadian Disruption as Mediator of Cardiometabolic Risk in Air PollutionR35ES031702 · NIEHS · CASE WESTERN RESERVE UNIVERSITY · PI Sanjay Rajagopalan · 2021 to 2026
$5.9M
Development of MRI microvascular biomarkers in cognitive impairment and dementiaUH2NS100588 · NINDS · JOHNS HOPKINS UNIVERSITY · PI ALBERT, MARILYN S., LU, HANZHANG · 2016 to 2018
$2.3M
Non-Contrast-Enhanced Velocity-Selective MR Angiography at 3T for Cerebrovascular DiseasesR01HL138182 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2018 to 2022
$2.0M
State of the Art 3T Research ScannerS10OD021648 · OD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2016 to 2016
$2.0M
Velocity-Selective Arterial Spin Labeling based Perfusion Mapping for Cerebrovascular DiseasesR01HL144751 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2019 to 2022
$1.7M
NON-CONTRAST-ENHANCED PERIPHERAL MR ANGIOGRAPHYR01HL135500 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI RAJAGOPALAN, SANJAY, WILSON, DAVID LYNN · 2017 to 2020
$1.5M
MRI-based Quantitative Brain Oximetry for Sickle Cell DiseaseK25HL145129 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI LI, WENBO · 2019 to 2021
$457k
NHLBI NIH HHS K25 HL145129NHLBI NIH HHS R01 HL135500NHLBI NIH HHS R01 HL138182NHLBI NIH HHS R01 HL144751NIBIB NIH HHS P41 EB015909NIBIB NIH HHS P41 EB031771NIEHS NIH HHS R35 ES031702NIH HHS K25 HL145129NIH HHS P41 EB015909NIH HHS R01 HL135500NIH HHS R01 HL138182NIH HHS R01 HL144751NIH HHS S10 OD021648NIH HHS UH2 NS100588NINDS NIH HHS UH2 NS100588
6 · The paper itself

Abstract

purposeBenchmarking of flow and perfusion MR techniques on standardized phantoms can facilitate the use of advanced angiography and perfusion-mapping techniques across multiple sites, field strength, and vendors. Here, MRA and perfusion mapping by arterial spin labeling (ASL) using Fourier transform (FT)-based velocity-selective saturation and inversion pulse trains were evaluated on a commercial perfusion phantom.

methodsThe FT velocity-selective saturation-based MRA and FT velocity-selective inversion-based ASL perfusion imaging were compared with time-of-flight and pseudo-continuous ASL at 3 T on the perfusion phantom at two controlled flow rates, 175 mL/min and 350 mL/min. Velocity-selective MRA (VSMRA) and velocity-selective ASL (VSASL) were each performed with three velocity-encoding directions: foot-head, left-right, and oblique 45°. The contrast-to-noise ratio for MRA scans and perfusion-weighted signal, as well as labeling efficiency for ASL methods, were quantified.

resultsOn this phantom with feeding tubes having only vertical and transverse flow directions, VSMRA and VSASL exhibited the dependence of velocity-encoding directions. The foot-head-encoded VSMRA and VSASL generated similar signal contrasts as time of flight and pseudo-continuous ASL for the two flow rates, respectively. The oblique 45°-encoded VSMRA yielded more uniform contrast-to-noise ratio across slices than foot-head and left-right-encoded VSMRA scans. The oblique 45°-encoded VSASL elevated labeling efficiency from 0.22-0.68 to 0.82-0.90 through more uniform labeling of the entire feeding tubes.

conclusionBoth FT velocity-selective saturation-based VSMRA and FT velocity-selective inversion-based VSASL were characterized on a commercial perfusion phantom. Careful selection of velocity-encoding directions along the major vessels is recommended for their applications in various organs.

Indexed as

Cerebrovascular CirculationMagnetic Resonance AngiographyAlgorithmsFourier AnalysisPerfusionSpin LabelsSpin Labelsarterial spin labelingFourier transform-based velocity-selective pulse trainmagnetic resonance angiographyphantomvelocity-selective inversionvelocity-selective saturation

Identifiers

PMID33934396
PMCPMC8861891

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.