Evidence map›Paper›PMID 33945886›Full record

Trial reportContemporary clinical trials2021

The Daily Activity Study of Health (DASH): A pilot randomized controlled trial to enhance physical activity in sedentary older adults.

Meishan Ai, Timothy P Morris, Cora Ordway, Elizabeth Quinoñez, Frank D'Agostino, Susan Whitfield-Gabrieli, Charles H Hillman, Dominika M Pindus, Edward McAuley, Nancy Mayo and 4 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04315363 (Changing and Understanding Motivation to Increase Physical Activity Among Sedentary Older Adults), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04315363 nacompletednot on this map

Changing and Understanding Motivation to Increase Physical Activity Among Sedentary Older Adults

TypeinterventionalSponsorNortheastern UniversityRan2020 to 2023Enrolled40ConditionsAgingArmsMotivational MRI and Behavioral Intervention, Control MRI and Behavioral Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Meishan AiDepartment of Psychology, Northeastern University, USA. Electronic address: ai.me@northeastern.edu.
Timothy P MorrisDepartment of Psychology, Northeastern University, USA.
Cora OrdwayDepartment of Psychology, Northeastern University, USA.
Elizabeth QuinoñezDepartment of Psychology, Northeastern University, USA.
Frank D'AgostinoHarvard University, USA.
Susan Whitfield-GabrieliDepartment of Psychology, Northeastern University, USA.
Charles H HillmanDepartment of Psychology, Northeastern University, USA; Department of Physical Therapy, Movement, & Rehabilitation Sciences, Northeastern University, USA.
Dominika M PindusDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, USA; Neuroscience Program, University of Illinois at Urbana-Champaign, USA.
Edward McAuleyDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, USA.
Nancy MayoDepartment of Neurology and Neurosurgery, McGill University, Canada.
Adrián Noriega de la ColinaDepartment of Neurology and Neurosurgery, McGill University, Canada.
Siobhan PhillipsDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, USA.
Arthur F KramerDepartment of Psychology, Northeastern University, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, USA.
Maiya GeddesDepartment of Neurology and Neurosurgery, McGill University, Canada; Brigham and Women's Hospital, Harvard Medical School, USA.
Northeastern University · USMcGill University · CAUniversity of Illinois Urbana-Champaign · USBrigham and Women's Hospital · USHarvard University Press · USNorthwestern University · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Core B - Pilot StudiesP30AG048785 · NIA · BRANDEIS UNIVERSITY · PI LACHMAN, MARGIE E · 2014 to 2023
$4.5M
NCATS NIH HHS UL1 TR001102NIA NIH HHS P30 AG048785
6 · The paper itself

Abstract

Sedentary behavior increases the risk for multiple chronic diseases, early mortality, and accelerated cognitive decline in older adults. Interventions to reduce sedentary behavior among older adults are needed to improve health outcomes and reduce the burden on healthcare systems. We designed a randomized controlled trial that uses a self-affirmation manipulation and gain-framed health messaging to effectively reduce sedentary behavior in older adults. This message-based intervention lasts 6 weeks, recruiting 80 healthy but sedentary older adults from the community, between the ages of 60 and 95 years. Participants are randomly assigned to one of two groups: 1) an intervention group, which receives self-affirmation followed by gain-framed health messages daily or 2) a control group, which receives daily loss-framed health messages only. Objective physical activity engagement is measured by accelerometers. Accelerometers are deployed a week before, during, and the last week of intervention to examine potential changes in sedentary time and physical activity engagement. Participants undertake structural and functional (resting and task-based) MRI scans, neuropsychological tests, computerized behavioral measures, and neurobehavioral inventories at baseline and after the intervention. A 3-month follow-up assesses the long-term maintenance of any engendered behaviors from the intervention period. This study will assess the effectiveness of a novel behavioral intervention at reducing sedentarism in older adults and examine the neurobehavioral mechanisms underlying any such changes.

Indexed as

ExerciseSedentary BehaviorAgedAged, 80 and overBehavior TherapyHumansMiddle AgedPilot ProjectsAffective psychologyfMRIPositive messagingRandomized controlled trialSedentary behaviorSelf-affirmation

Identifiers

PMID33945886
PMCPMC8845050
OpenAlexW3157431328

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.