Evidence map›Paper›PMID 33946271›Full record

ReviewInternational journal of molecular sciences2021

Mitochondria: Insights into Crucial Features to Overcome Cancer Chemoresistance.

Ilaria Genovese, Marianna Carinci, Lorenzo Modesti, Gianluca Aguiari, Paolo Pinton, Carlotta Giorgi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Multilevel Mechanisms of Cancer Drug Resistance.International journal of molecular sciences · 2024
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Influence of Tariquidar, an ABC Transporter Inhibitor, on the CaPharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
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  16. Article
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  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ilaria GenoveseDepartment of Medical Sciences, Section of Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-1981-750X
Marianna CarinciDepartment of Medical Sciences, Section of Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.
Lorenzo ModestiDepartment of Medical Sciences, Section of Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.
Gianluca AguiariDepartment of Neuroscience and Rehabilitation, Section of Biochemistry, Molecular Biology and Genetics, University of Ferrara, 44121 Ferrara, Italy.
Paolo PintonDepartment of Medical Sciences, Section of Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-7108-6508
Carlotta GiorgiDepartment of Medical Sciences, Section of Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.
University of Ferrara · IT

Funding

Italian Association for Cancer Research (AIRC) IG19803Italian Association for Cancer Research (AIRC) IG23670Italian Association for Cancer Research (AIRC) "Acqua Vitasnella" 22552Progetti di Rilevante Interesse Nazionale PRIN20177E9EPYProgetti di Rilevante Interesse Nazionale PRIN2017E5L5P3
6 · The paper itself

Abstract

Mitochondria are key regulators of cell survival and are involved in a plethora of mechanisms, such as metabolism, Ca

Indexed as

AnimalsAntineoplastic AgentsCalcium SignalingCell SurvivalDrug Resistance, NeoplasmHumansMitochondriaMitochondrial DynamicsMitochondrial ProteinsMitophagyNeoplasmsOxidative StressAntineoplastic AgentsMitochondrial Proteinscancerdrug resistancemetabolic plasticitymitochondrial Ca2+ homeostasismitochondrial dynamics

Identifiers

PMID33946271
PMCPMC8124268
OpenAlexW3158700157

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.