Evidence map›Paper›PMID 33946864›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Diet-Derived Antioxidants and Their Role in Inflammation, Obesity and Gut Microbiota Modulation.

Andrea Deledda, Giuseppe Annunziata, Gian Carlo Tenore, Vanessa Palmas, Aldo Manzin, Fernanda Velluzzi

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 2 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 2 syntheses or guidelines pooled it, 137 citations in OpenAlex.

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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrea DeleddaObesity Unit, Department of Medical Sciences and Public Health, University of Cagliari, Ospedale San Giovanni di Dio, Via Ospedale 54, 09124 Cagliari, Italy.ORCID 0000-0001-6925-7515
Giuseppe AnnunziataDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-1922-662X
Gian Carlo TenoreDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-0251-9936
Vanessa PalmasMicrobiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Aldo ManzinMicrobiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.ORCID 0000-0003-2961-3428
Fernanda VelluzziObesity Unit, Department of Medical Sciences and Public Health, University of Cagliari, Ospedale San Giovanni di Dio, Via Ospedale 54, 09124 Cagliari, Italy.
University of Cagliari · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is generally accepted that gut microbiota, inflammation and obesity are linked to the development of cardiovascular diseases and other chronic/non-communicable pathological conditions, including cancer, neurodegenerative diseases and ageing-related disorders. In this scenario, oxidative stress plays a pivotal role. Evidence suggests that the global dietary patterns may represent a tool in counteracting oxidative stress, thus preventing the onset of diseases related to oxidative stress. More specifically, dietary patterns based on the regular consumption of fruits and vegetables (i.e., Mediterranean diet) have been licensed by various national nutritional guidelines in many countries for their health-promoting effects. Such patterns, indeed, result in being rich in specific components, such as fiber, minerals, vitamins and antioxidants, whose beneficial effects on human health have been widely reported. This suggests a potential nutraceutical power of specific dietary components. In this manuscript, we summarize the most relevant evidence reporting the impact of dietary antioxidants on gut microbiota composition, inflammation and obesity, and we underline that antioxidants are implicated in a complex interplay between gut microbiota, inflammation and obesity, thus suggesting their possible role in the development and modulation of chronic diseases related to oxidative stress and in the maintenance of wellness. Do all roads lead to Rome?

Indexed as

ageingantioxidantsgut microbiotainflammationnutraceuticalobesityoxidative stresspolyphenols

Identifiers

PMID33946864
PMCPMC8146040
OpenAlexW3157190253

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.