Evidence map›Paper›PMID 33947083›Full record

ArticleBiomedicines2021

Amphetamine-Decreased Progesterone and Estradiol Release in Rat Granulosa Cells: The Regulatory Role of cAMP- and Ca

Chung-Yu Chen, Chien-Rung Chen, Chiao-Nan Chen, Paulus S Wang, Toby Mündel, Yi-Hung Liao, Shiow-Chwen Tsai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Chung-Yu ChenDepartment of Exercise and Health Sciences, University of Taipei, Taipei City 111, Taiwan.
Chien-Rung ChenDepartment of Nursing, Cardinal Tien Junior College of Healthcare and Management, New Taipei City 231, Taiwan.
Chiao-Nan ChenDepartment of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei City 112, Taiwan.ORCID 0000-0001-9299-0192
Paulus S WangDepartment of Physiology, National Yang Ming Chiao Tung University, Taipei City 112, Taiwan.
Toby MündelSchool of Sport, Exercise and Nutrition, Massey University, Palmerston North 4442, New Zealand.ORCID 0000-0002-4214-8543
Yi-Hung LiaoDepartment of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei City 112, Taiwan.
Shiow-Chwen TsaiInstitute of Sports Sciences, University of Taipei, Taipei City 112, Taiwan.
National Yang Ming Chiao Tung University · TWAsia University · TWMassey University · NZNational Taipei University of Nursing and Health Science · TWUniversity of Taipei · TW

Funding

Ministry of Science and Technology, Taiwan NSC 95-2320-B-341 -001Taiwan Food and Drug Administration DOH92-NNB-1013
6 · The paper itself

Abstract

The purpose of this study is to evaluate the amphetamine effects on progesterone and estradiol production in rat granulosa cells and the underlying cellular regulatory mechanisms. Freshly dispersed rat granulosa cells were cultured with various test drugs in the presence of amphetamine, and the estradiol/progesterone production and the cytosolic cAMP level were measured. Additionally, the cytosolic-free Ca

Indexed as

follicle-stimulating hormone (FSH) administrationprotein kinase A (PKA), L-type calcium channelreproductive hormonessteroidogenic enzymes

Identifiers

PMID33947083
PMCPMC8145484
OpenAlexW3157497447

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.