Evidence map›Paper›PMID 33947251›Full record

ReviewInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2022

P2Y12 inhibitors for the neurointerventionalist.

Robin J Borchert, Davide Simonato, Charlotte R Hickman, Maurizio Fuschi, Lucie Thibault, Hans Henkes, David Fiorella, Benjamin Yq Tan, Leonard Ll Yeo, Hegoda L D Makalanda and 2 more

Abstract readReview
In one paragraph

Review in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Safety of dual antiplatelet therapy using aspirin and low-dose Prasugrel with platelet reactivity testing in flow diverter treatment of intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Ticagrelor versus clopidogrel in stent-assisted coil embolization of unruptured intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Robin J BorchertDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-4673-9746
Davide SimonatoDepartment of Neuroradiology, Oxford University Hospital NHS Foundation Trust, Oxford, UK.ORCID https://orcid.org/0000-0003-3601-9136
Charlotte R HickmanAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Maurizio FuschiDepartment of Neuroradiology, Oxford University Hospital NHS Foundation Trust, Oxford, UK.
Lucie ThibaultWFITN Scientific Committee Member, Paris, France.
Hans HenkesClinic for Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany.
David FiorellaClinic for Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany.
Benjamin Yq TanClinic for Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany.
Leonard Ll YeoClinic for Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany.ORCID https://orcid.org/0000-0002-4249-0402
Hegoda L D MakalandaRoyal London Hospital, London, UK.
Ken WongRoyal London Hospital, London, UK.
Pervinder BhogalClinic for Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany.ORCID https://orcid.org/0000-0002-5514-5237

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of antiplatelets is widespread in clinical practice. However, for neurointerventional procedures, protocols for antiplatelet use are scarce and practice varies between individuals and institutions. This is further complicated by the quantity of antiplatelet agents which differ in route of administration, dosage, onset of action, efficacy and ischemic and hemorrhagic complications. Clarifying the individual characteristics for each antiplatelet agent, and their associated risks, will increasingly become relevant as the practice of mechanical thrombectomy, stenting, coiling and flow diversion procedures grows. The aim of this review is to summarize the existing literature for the use of P2Y12 inhibitors in neurointerventional procedures, examine the quality of the evidence, and highlight areas in need of further research.

Indexed as

Endovascular ProceduresHumansPlatelet Aggregation InhibitorsStentsPlatelet Aggregation InhibitorsaneurysmAntiplateletshemorrhagestrokethrombectomy

Identifiers

PMID33947251
PMCPMC8905084

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.