Evidence map›Paper›PMID 33947370›Full record

ArticleBMC psychiatry2021

Cognitive control and emotional response in attention-deficit/ hyperactivity disorder comorbidity with disruptive, impulse-control, and conduct disorders.

Yuncheng Zhu, Li Liu, Daoliang Yang, Haifeng Ji, Tianming Huang, Lianxue Xue, Xixi Jiang, Kaiyun Li, Lily Tao, Qing Cai and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Yuncheng ZhuShanghai Hongkou Mental Health Center, Shanghai, 200083, China.
Li LiuShanghai Changning Mental Health Center, Shanghai, 200335, China.
Daoliang YangShanghai Changning Mental Health Center, Shanghai, 200335, China.
Haifeng JiShanghai Changning Mental Health Center, Shanghai, 200335, China.
Tianming HuangShanghai Changning Mental Health Center, Shanghai, 200335, China.
Lianxue XueShanghai Changning Mental Health Center, Shanghai, 200335, China.
Xixi JiangShanghai Changning Mental Health Center, Shanghai, 200335, China. 226334295@qq.com.
Kaiyun LiUniversity of Jinan, Shandong Province, Jinan, 250022, China.
Lily TaoKey Laboratory of Brain Functional Genomics (MOE & STCSM), Shanghai Changning-ECNU Mental Health Center, Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University, Shanghai, 200062, China.
Qing CaiKey Laboratory of Brain Functional Genomics (MOE & STCSM), Shanghai Changning-ECNU Mental Health Center, Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University, Shanghai, 200062, China.
Yiru FangClinical Research Center, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. yirufang@aliyun.com.
Shanghai Changning Mental Health Center · CNEast China Normal University · CNCenter for Excellence in Brain Science and Intelligence Technology · CNShanghai Jiao Tong University · CNUniversity of Jinan · CN

Funding

the Research Project of Shanghai Changning District Science and Technology Commission CNKW2018Y23
6 · The paper itself

Abstract

backgroundThis study investigated cognitive and emotional functioning in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and disruptive, impulse-control, and conduct disorders (DICCD).

methodsThirty patients with ADHD, 26 with DICCD, 22 with ADHD+DICCD were recruited from the outpatient department of Shanghai Changning Mental Health Center, plus 20 healthy controls (HC). Differences between the groups in cognitive and emotional functioning were examined using Golden's Stroop and Emotional Stroop tests. For Emotional Stroop Mean reaction time (RT) of positive word (POS) and negative word (NEG) with color congruence (C) or incongruence (I) were recorded as POS-C, POS-I, NEG-C and NEG-I, respectively.

resultsFor Golden's interference scores (IGs), both errors and RTs in the ADHD group were higher than in the other groups. Longer mean RTs of POS-C, POS-I, NEG-C and neural word (NEU) of the ADHD group, and NEG-I of ADHD+DICCD and DICCD groups were observed compared to HC. After 12 weeks of methylphenidate treatment, differences between ADHD subgroups and HC on Golden's Stroop RT disappeared, but differences in Golden's Stroop errors and Emotional Stroop mean RTs remained. The ADHD+DICCD group showed longer mean RTs in NEG-C, NEG-I and NEU of the Emotional Stroop test than the ADHD group.

conclusionsOur study shows that regardless of emotional responding, deficit in cognitive control is the core symptom of ADHD. However, emotionally biased stimuli may cause response inhibitory dysfunction among DICCD with callous-unemotional traits, and the comorbidity of ADHD and DICCD tends to account for the negative emotional response characteristic of DICCD. These deficits may be eliminated by medication treatment in ADHD, but not the ADHD with comorbid DICCD. Our results support the notion that ADHD with comorbid DICCD is more closely related to DICCD than to ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityConduct DisorderAdolescentAttentionChildChinaCognitionComorbidityEmotionsHumansNeuropsychological TestsAttention-deficit/hyperactivity disorderCognitive controlDisruptive, impulse-control, and conduct disordersNeural networkStroop effect

Identifiers

PMID33947370
PMCPMC8094501
OpenAlexW3158177094

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.