Evidence map›Paper›PMID 33947722›Full record

ReviewDiabetes2021

Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research.

Mollie S H Friedlander, Vy M Nguyen, Seung K Kim, Romina J Bevacqua

Abstract readReview
In one paragraph

Review in Diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mollie S H FriedlanderDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA.
Vy M NguyenDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA.
Seung K KimDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA bevacqua@stanford.edu seungkim@stanford.edu.ORCID 0000-0001-6135-7810
Romina J BevacquaDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA bevacqua@stanford.edu seungkim@stanford.edu.

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
TLI/ATG CONDTIONING: KIDNEY/BLOOD STEM CELL TRANSPLANTSP01HL075462 · NHLBI · STANFORD UNIVERSITY · PI MEYER, EVERETT · 2004 to 2020
$27.9M
Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
GENETICS TRAINING PROGRAM FOR PHD CANDIDATEST32GM007790 · NIGMS · STANFORD UNIVERSITY · PI BRUNET, ANNE, KINGSLEY, DAVID M · 1985 to 2020
$12.8M
Human Pancreas Analysis Program-T2DU01DK123716 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ATKINSON, MARK A., BOTTINO, RITA · 2019 to 2024
$6.6M
Therapeutic targeting of human islets with recombinant regulatory T cellsU01DK123743 · NIDDK · STANFORD UNIVERSITY · PI KIM, SEUNG K, MEYER, EVERETT · 2019 to 2022
$2.9M
Genetic and physiologic regulation of pig islet development and functionR01DK128932 · NIDDK · STANFORD UNIVERSITY · PI BERGER, TRISH, KIM, SEUNG K · 2021 to 2024
$2.6M
In vivo systems to discover mechanisms regulating human islet alpha cell functionR01DK126482 · NIDDK · STANFORD UNIVERSITY · PI KIM, SEUNG K, MACDONALD, PATRICK · 2020 to 2023
$2.2M
Regulation of gastrointestinal hormone signaling and metabolism by Neuromedin UR01DK107507 · NIDDK · STANFORD UNIVERSITY · PI KIM, SEUNG K · 2017 to 2021
$2.0M
Discovering genetic and hormonal mechanisms underlying diabetes risk from flies to humansR01DK108817 · NIDDK · STANFORD UNIVERSITY · PI KIM, SEUNG K · 2018 to 2022
$2.0M
Howard Hughes Medical InstituteNHLBI NIH HHS P01 HL075462NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK116074NIDDK NIH HHS R01 DK107507NIDDK NIH HHS R01 DK108817NIDDK NIH HHS R01 DK126482NIDDK NIH HHS R01 DK128932NIDDK NIH HHS U01 DK123716NIDDK NIH HHS U01 DK123743NIGMS NIH HHS T32 GM007790
6 · The paper itself

Abstract

Pancreatic islets are vital endocrine regulators of systemic metabolism, and recent investigations have increasingly focused on understanding human islet biology. Studies of isolated human islets have advanced understanding of the development, function, and regulation of cells comprising islets, especially pancreatic

Indexed as

AnimalsHumansInsulin-Secreting CellsIslets of LangerhansIslets of Langerhans TransplantationOrganoids

Identifiers

PMID33947722
PMCPMC8343609

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.