Evidence map›Paper›PMID 33948825›Full record

SynthesisJournal of autism and developmental disorders2022

A Meta-analysis of Gut Microbiota in Children with Autism.

Pedro Andreo-Martínez, María Rubio-Aparicio, Julio Sánchez-Meca, Alejandro Veas, Agustín Ernesto Martínez-González

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Microbiota in Autism Spectrum Disorder: A Systematic Review.International journal of molecular sciences · 2023
    Pooled it
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  8. Review
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  14. Observational
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  18. Validation of the Pain and Sensitivity Reactivity Scale in Neurotypical Late Adolescents and Adults.European journal of investigation in health, psychology and education · 2025
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pedro Andreo-MartínezDepartment of Agricultural Chemistry, Faculty of Chemistry, University of Murcia, Campus of Espinardo, Murcia, Spain.ORCID http://orcid.org/0000-0001-6535-5492
María Rubio-AparicioDepartment of Health Psychology, Faculty of Health Sciences, University of Alicante, Alicante, Spain.ORCID http://orcid.org/0000-0002-2599-4246
Julio Sánchez-MecaDepartment Basic Psychology and Methodology, Faculty of Psychology, University of Murcia, Murcia, Spain.ORCID http://orcid.org/0000-0002-8412-788X
Alejandro VeasDepartment of Developmental Psychology and Didactics, Faculty of Education, University of Alicante, Alicante, Spain.ORCID http://orcid.org/0000-0002-5560-2215
Agustín Ernesto Martínez-GonzálezDepartment of Developmental Psychology and Didactics, Faculty of Education, University of Alicante, Alicante, Spain. agustin.emartinez@ua.es.ORCID http://orcid.org/0000-0002-9576-7348

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have reported dysbiosis in the gut microbiota (GM) of children with autism spectrum disorders (ASD), which may be a determining factor on child development through the microbiota-gut-brain axis. However, it is not clear if there is a specific group of dysbiotic bacteria in ASD. The aim of this study was to carry out a meta-analysis on the studies that analyze GM in children with ASD. 18 studies fulfilled our selection criteria. Our results showed a lower relative abundance of Streptococcus (SMD

Indexed as

Autism Spectrum DisorderAutistic DisorderGastrointestinal MicrobiomeBacteriaChildDysbiosisHumansAutism spectrum disorders (ASD)Gut microbiotaMeta-analysisMicrobiota-gut-brain axisSystematic review

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.