Evidence mapPaperPMID 33958013Full record

ArticlePublic health nutrition2022

Antioxidant and inflammatory potential of diet among women at risk of cervical cancer: findings from a cross-sectional study in Italy.

Andrea Maugeri, Martina Barchitta, Roberta Magnano San Lio, Aurora Scalisi, Antonella Agodi

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Article in Public health nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  8. The dietary inflammatory index (DIIBMC public health · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. The effects of dietary supplements in patients with cervical cancer: a comprehensive systematic review.European journal of obstetrics & gynecology and reproductive biology: X · 2023
    Review
  13. Article
  14. How COVID-19 Pandemic Has Influenced Public Interest in Foods: A Google Trends Analysis of Italian Data.International journal of environmental research and public health · 2023
    Article
  15. Article
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Andrea MaugeriDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Via Santa Sofia 87, 95123Catania, Italy.
Martina BarchittaDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Via Santa Sofia 87, 95123Catania, Italy.
Roberta Magnano San LioDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Via Santa Sofia 87, 95123Catania, Italy.
Aurora ScalisiCervical Cancer Screening Unit, Azienda Sanitaria Provinciale of Catania, Catania, Italy.
Antonella AgodiDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Via Santa Sofia 87, 95123Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the association of Composite Dietary Antioxidant Index (CDAI) and Dietary Inflammatory Index (DII) with the prevalence of high-grade cervical intraepithelial neoplasia (CIN).

designA cross-sectional study was conducted on women with abnormal Papanicolaou test, who underwent high-risk human papillomavirus (HPV) screening and histological test through colposcopy. Dietary data were collected using a FFQ and used to assess both CDAI and DII.

settingWomen were recruited from 2012 to 2015 at the Cervical Cancer Screening Unit of the 'Azienda Sanitaria Provinciale' of Catania (Italy).

participantsThe study included 539 women with a mean age of 40·2 years, who were classified as cases (n 127 with CIN2 or more severe lesions) and controls (n 412 with normal cervical epithelium or CIN1).

resultsAlthough we observed a lower proportion of HPV-positive women among those with higher CDAI (P < 0·001), the index was not associated with the diagnosis of CIN2 or more severe lesions. By contrast, women with medium or high DII showed higher odds to be diagnosed with CIN2 or more severe lesions than those with low DII (OR = 2·15; 95 % CI 1·11, 4·17; P = 0·024 and OR = 3·14; 95 % CI 1·50, 6·56; P = 0·002, respectively), after adjusting for age, HPV status, educational level, BMI, smoking status, parity, use of oral contraceptives and supplements.

conclusionsOur findings suggested that a pro-inflammatory diet might be associated with an increased risk of CIN2 and more severe lesions. However, further prospective studies should be encouraged to support this evidence.

Indexed as

Papillomavirus InfectionsUterine Cervical NeoplasmsAdultAntioxidantsCross-Sectional StudiesDietEarly Detection of CancerFemaleHumansPapillomaviridaePregnancyProspective StudiesAntioxidantsDietHPV infectionInflammationNutritional epidemiologyOxidative stress

Identifiers

PMID33958013
PMCPMC9991670

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.