SynthesisPloS one2021
Diagnostic accuracy of point-of-care ultrasound for pulmonary tuberculosis: A systematic review.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 44 citations in OpenAlex.
- Reply to "Lung Ultrasound in the Diagnosis of Pleural Tuberculosis".JMA journal · 2026Article
- Lung ultrasound and the interstitial syndrome in tuberculosis endemic regions: illustrated insights from diverse clinical settings.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Review
- The role of medical imaging in translational research into early pulmonary tuberculosis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026Review
- Artificial Intelligence for Tuberculosis Screening and Detection: From Evidence to Policy and Implementation.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Development of a clinical algorithm-based scoring system to diagnose smear-negative pulmonary tuberculosis in Sabah, Malaysia using the modified Delphi method.Journal of global health · 2026Article
- Tuberculous Pleurisy Detected by Lung Ultrasound.JMA journal · 2026Article
- Tuberculosis Visualized With the Ultrasound Probe: A Systematic Review of Sonographic Pattern Descriptions and an Analysis of Common Sonographic Features.Open forum infectious diseases · 2025Review
- Lung and abdominal ultrasound accuracy for tuberculosis: An Indian prospective cohort study.PloS one · 2025Article
- Development and validation of a nomogram predicting multidrug-resistant tuberculosis risk in East China.PeerJ · 2025Article
- Diagnostic Accuracy of Lung and Abdominal Ultrasound for Tuberculosis in a German Multicenter Cohort of Patients With Presumed Tuberculosis Disease.Open forum infectious diseases · 2024Article
- Assessment of radiological capacity and disparities in TB diagnosis: a comparative study of Mozambique, South Africa and Spain.BMJ public health · 2024Article
- Subtle Sonographic Signs of Disseminated Tuberculosis: A Case Report and Narrative Literature Review.The American journal of tropical medicine and hygiene · 2024Review
- Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations.Diagnostics (Basel, Switzerland) · 2024Review
- Use of a Handheld Ultrasonographic Device to Identify Heart Failure and Pulmonary Disease in Rural Africa.JAMA network open · 2024Article
- Comparison of chest ultrasound features to chest radiography in the diagnosis for pediatric tuberculosis: a cross-sectional study.The Pan African medical journal · 2024Article
- Article
- The Role of Ultrasound in the Diagnosis of Pulmonary Infection Caused by Intracellular, Fungal Pathogens and Mycobacteria: A Systematic Review.Diagnostics (Basel, Switzerland) · 2023Review
- Diagnostic accuracy of chest ultrasound scan in the diagnosis of childhood tuberculosis.PloS one · 2023Article
- Extrapulmonary tuberculosis mortality according to clinical and point of care ultrasound features in Mozambique.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The advent of affordable, portable ultrasound devices has led to increasing interest in the use of point-of-care ultrasound (POCUS) for the detection of pulmonary TB (PTB). We undertook a systematic review of the diagnostic accuracy of POCUS for PTB. Five databases were searched for articles published between January 2010 and June 2020. Risk of bias was assessed using QUADAS-2. Data on sensitivity and specificity of individual lung ultrasound findings were collected, with variable reference standards including PCR and sputum smear microscopy. Six of 3,919 reviewed articles were included: five in adults and one in children, with a total sample size of 564. Studies had high risk of bias in many domains. In adults, subpleural nodule and lung consolidation were the lung ultrasound findings with the highest sensitivities, ranging from 72.5% to 100.0% and 46.7% to 80.4%, respectively. Only one study reported specificity data. Variability in sensitivity may be due to variable reference standards or may imply operator dependence. There is insufficient evidence to judge the diagnostic accuracy of POCUS for PTB. There is also no consensus on the optimal protocols for acquiring and analysing POCUS images for PTB. New studies which minimise potential sources of bias are required to further assess the diagnostic accuracy of POCUS for PTB.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.