Evidence map›Paper›PMID 33964050›Full record

ArticleInternational journal of experimental pathology2021

The role of caveolin-1 and endothelial nitric oxide synthase polymorphisms in susceptibility to prostate cancer.

Mahdieh Aliyari, Daniel Elieh Ali Komi, Amir Kiani, Mahmoudreza Moradi, Maryam Tanhapour, Zohreh Rahimi, Hadi Mozafari, Ehsan Mohammadi-Noori, Tayebeh Pourmotabbed, Asad Vaisi-Raygani and 1 more

Open access · greenAbstract read
In one paragraph

Article in International journal of experimental pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Mahdieh AliyariFertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0003-2270-1169
Daniel Elieh Ali KomiCellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran.ORCID 0000-0003-0546-5280
Amir KianiRegenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-7802-2117
Mahmoudreza MoradiRegenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-4989-5250
Maryam TanhapourFertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-3098-9564
Zohreh RahimiMedical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0001-7589-3307
Hadi MozafariMedical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0003-4428-7675
Ehsan Mohammadi-NooriPharmaceutical Sciences Research Center, Health Institute Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-1464-2691
Tayebeh PourmotabbedDepartment of Microbiology, Immunology, Biochemistry, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0003-3468-5880
Asad Vaisi-RayganiFertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-3042-2832
Fariborz BahrehmandMedical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0003-3866-6847
Kermanshah University of Medical Sciences · IRUniversity of Tennessee Health Science Center · USUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caveolin-1(cav-1) is overexpressed in prostate cancer (PC) and is associated with progression of the disease. We investigated the effects of CAV1-T29107A and endothelial nitric oxide synthase (eNOS) G894T polymorphisms on the serum levels of testosterone, NO and prostate-specific antigen (PSA) in patients with PC. We genotyped cav-1 and eNOS genes in 112 PC patients and 150 healthy controls by PCR-RFLP. Serum levels of

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAgedAllelesCase-Control StudiesCaveolin 1Gene FrequencyHumansMaleMiddle AgedNitric Oxide Synthase Type IIIProstate-Specific AntigenProstatic NeoplasmsTestosteroneCaveolin 1Nitric Oxide Synthase Type IIIProstate-Specific AntigenTestosteronecaveolin-1diabeteseNOSprostate cancerPSAsmokingtestosterone

Identifiers

PMID33964050
PMCPMC8626621
OpenAlexW3159398380

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.