Evidence map›Paper›PMID 33964510›Full record

SynthesisThe journal of allergy and clinical immunology. In practice2021

A Systematic Review of the Effect of Physical Activity on Asthma Outcomes.

Margaret M Kuder, Maureen Clark, Caitlin Cooley, Valentin Prieto-Centurion, Adam Danley, Isaretta Riley, Aminaa Siddiqi, Katherine Weller, Spyros Kitsiou, Sharmilee M Nyenhuis

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05726487 (ACTION), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05726487 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

ACTION (physicAl aCtiviTy In minOrity womeN With Asthma) Intervention: Efficacy to Implementation

TypeinterventionalSponsorUniversity of ChicagoRan2023 to 2026Enrolled224ConditionsAsthmaArmsACTION Intervention, Education Control
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Dog exposure and subsequent asthma outcomes in children with asthma and allergy.The journal of allergy and clinical immunology. Global · 2026
    Article
  6. Life's Essential 8 and cardiovascular health: Protective effects on chronic respiratory diseases.International journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Association of daily steps over time with adult asthma incidence.The Journal of allergy and clinical immunology · 2025
    Article
  12. Article
  13. Article
  14. Observational
  15. Review
  16. Patient-centred outcomes in severe asthma: fatigue, sleep, physical activity and work.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Margaret M KuderRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
Maureen ClarkLibrary of the Health Sciences, University of Illinois at Chicago, Chicago, Ill; Department of Medical Education, University of Illinois at Chicago, Chicago, Ill.
Caitlin CooleyDepartment of Medicine, University of Illinois at Chicago, Chicago, Ill.
Valentin Prieto-CenturionDepartment of Medicine, University of Illinois at Chicago, Chicago, Ill.
Adam DanleyDepartment of Medicine, University of Illinois at Chicago, Chicago, Ill.
Isaretta RileyDepartment of Medicine, Duke University, Durham, NC.
Aminaa SiddiqiDepartment of Pediatrics, Stanford University, Palo Alto, Calif.
Katherine WellerRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
Spyros KitsiouDepartment of Biomedical and Health Information Sciences, University of Illinois at Chicago, Chicago, Ill.
Sharmilee M NyenhuisDepartment of Medicine, University of Illinois at Chicago, Chicago, Ill. Electronic address: snyenhui@uic.edu.

Funding

Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu · 2017 to 2026
$13.6M
ACTION, A lifestyle physiCal acTivity Intervention for MinOrity womeN with asthma: From Efficacy to ImplementationR01MD017277 · NIMHD · UNIVERSITY OF CHICAGO · PI Sharmilee Maria Nyenhuis · 2022 to 2026
$3.4M
Coping with Asthma through Life Management (CALM)K01HL159043 · NHLBI · DUKE UNIVERSITY · PI RILEY, ISARETTA · 2021 to 2025
$808k
ACTION Intervention: Physical Activity in Minority Women with AsthmaK01HL133370 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NYENHUIS, SHARMILEE MARIA · 2016 to 2019
$741k
NHLBI NIH HHS K01 HL133370NHLBI NIH HHS K01 HL159043NIEHS NIH HHS P30 ES027792NIMHD NIH HHS R01 MD017277
6 · The paper itself

Abstract

backgroundAsthma is a chronic respiratory disease that affects millions worldwide. Medication management is the current mainstay of treatment; however, there is evidence to suggest additional benefit with lifestyle changes, particularly with increased physical activity.

objectiveTo discover and evaluate the effects of physical activity on asthma outcomes.

methodsSystematic search of PubMed, Excerpta Medica database, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Rehabilitation and Sports Medicine Source, Scopus, and Web of Science identified 11,155 results. Thirty-five articles met our inclusion criteria spanning 20 studies. Data extraction was conducted by 6 independent reviewers, and final results were evaluated by a seventh reviewer and the senior author.

resultsWide variation among selected studies, including the heterogeneity of interventions and outcome variables, did not support a meta-analysis. Mixed results of the effects of physical activity on asthma outcomes were found. Most studies suggest that physical activity improves asthma control, quality of life, lung function parameters, and inflammatory serologies, whereas 3 found no improvements in any of these outcomes. No studies reported worsening asthma outcomes.

conclusionsThis review highlights the emerging and promising role of physical activity as a nonpharmacologic treatment for asthma. Additional high-quality randomized controlled trials are needed to overcome the problems of measurement heterogeneity and the dilution of outcome effect size measurement related to physical activity interventions for asthma.

Indexed as

AsthmaQuality of LifeExerciseHumansLife StyleAsthmaControlExerciseInflammationPhysical activityQuality of life

Identifiers

PMID33964510
PMCPMC8434961

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.