ReviewCurrent opinion in endocrinology, diabetes, and obesity2021
Sleep disruptions and bone health: what do we know so far?
Review in Current opinion in endocrinology, diabetes, and obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Impact of sleep duration on bone mineral density and osteoporosis risk: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Review
- An intelligent auxiliary diagnostic system for early osteoporosis screening using stacking ensemble learning.BMC medical informatics and decision making · 2026Article
- Review
- Neurokinin Antagonists to Treat Vasomotor Symptoms-Possible Implications for Long-Term Health and Disease.Journal of clinical medicine · 2025Article
- Association between sleep duration and hip fracture risk among the older adults: a cross-sectional study based on the NHANES.BMC musculoskeletal disorders · 2025Article
- Association between life's essential 8 and bone mineral density among adults aged 20-59 years.Scientific reports · 2025Article
- Association of caffeine intake and sleep duration with bone mineral density: a cross-sectional study from National Health and Nutrition Examination Survey between 2011 and 2018.BMC musculoskeletal disorders · 2025Article
- Effect of electroacupuncture on restoration of traumatic vertebral compression fracture: two case studies and literature review.Frontiers in medicine · 2025Article
- 24-hour activity composition is associated with lower fall and fracture risk in older men.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Influence of sedentary behavior and physical activity in leisure and work on sleep duration: data from NHANES 2017-2018.Journal of activity, sedentary and sleep behaviors · 2024Article
- Association of Self-Reported Sleep Characteristics and Hip Fracture: Observational and Mendelian Randomization Studies.Healthcare (Basel, Switzerland) · 2023Article
- Sleep Disruption and Bone Health.Current osteoporosis reports · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThis review briefly summarizes the growing body of literature addressing the skeletal consequences of sleep and circadian disruption. RECENT
findingsThe most recent data in the field suggest that the diurnal variation in bone turnover markers are because of endogenous circadian rhythmicity linked to clock genes in all bone cells; in a small human intervention study, cumulative sleep restriction with concurrent circadian disruption negatively alter bone turnover markers in a way that could explain the lower BMD and increased fracture risk identified in some prior night shift work studies; abnormal sleep duration and obstructive sleep apnea are associated with low BMD and increased fracture risk in some but not all studies. SUMMARY: Normal physiology and some animal and human intervention studies suggest that sleep and circadian disruptions, such as night shift work, abnormal sleep durations and obstructive sleep apnea are detrimental to skeletal health. However, additional research in this area is needed to determine which sleep/circadian disturbances are most detrimental to skeletal health, the reversibility of such impairments, and underlying mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.