Evidence map›Paper›PMID 33972341›Full record

ArticleBMJ open2021

Pulmonary hypertension and home-based (PHAHB) exercise intervention: protocol for a feasibility study.

Ciara McCormack, Brona Kehoe, Sarah J Hardcastle, Noel McCaffrey, Andrew McCarren, Sean Gaine, Brian McCullagh, Niall Moyna

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05947240 (Effects of Upper Extremity Aerobic Exercise on Exercise Capacity and Physical Activity in Patients With Pulmonary Arterial Hypertension.), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05947240 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Upper Extremity Aerobic Exercise on Exercise Capacity and Physical Activity in Patients With Pulmonary Arterial Hypertension.

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled26ConditionsPulmonary Arterial Hypertension (PAH)Armsaerobic exercises, active alternating movements for the upper limbs
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. New trends in pulmonary hypertension.European respiratory review : an official journal of the European Respiratory Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ciara McCormackSchool of Health and Human Performance, Dublin City University, Dublin, Ireland ciara.mccormack26@mail.dcu.ie.ORCID 0000-0003-4508-5522
Brona KehoeDepartment of Sport & Exercise Science, Waterford Institute of Technology, Waterford, Ireland.
Sarah J HardcastleSchool of Health and Human Performance, Dublin City University, Dublin, Ireland.
Noel McCaffreyExWell Medical, Dublin, Ireland.
Andrew McCarrenInsight Centre for Data Analytics, Dublin City University, Dublin, Ireland.
Sean GaineRespiratory Department, Mater Misericordiae University Hospital, Dublin, Ireland.
Brian McCullaghRespiratory Department, Mater Misericordiae University Hospital, Dublin, Ireland.
Niall MoynaSchool of Health and Human Performance, Dublin City University, Dublin, Ireland.
Dublin City University · IEMater Misericordiae University Hospital · IEWaterford Institute of Technology · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNovel therapies for pulmonary hypertension (PH) have improved survival and slowed disease progression. However, patients still present with symptoms of exertional dyspnoea and fatigue, which impacts their ability to perform activities of daily living, reduces exercise tolerance and impairs their quality of life (QoL). Exercise training has shown to be safe and effective at enhancing QoL and physical function in PH patients, yet it remains an underused adjunct therapy. Most exercise training for PH patients has been offered through hospital-based programmes. Home-based exercise programmes provide an alternative model that has the potential to increase the availability and accessibility of exercise training as an adjunct therapy in PH. The purpose of this study is to investigate the feasibility, acceptability, utility and safety of a novel remotely supervised home-based PH exercise programme.

methodsSingle arm intervention with a pre/post comparisons design and a follow-up maintenance phase will be employed. Eligible participants (n=25) will be recruited from the Mater Misericordiae University Hospital PH Unit. Participants will undergo a 10-week home-based exercise programme, with induction training, support materials, telecommunication support and health coaching sessions followed by a 10-week maintenance phase. The primary outcomes are feasibility, acceptability, utility and safety of the intervention. Secondary outcomes will include the impact of the intervention on exercise capacity, physical activity, strength, health-related QoL and exercise self-efficacy. ETHICS AND DISSEMINATION: Ethics approval has been obtained from the Mater Misericordiae Institutional Review Board REF:1/378/2032 and Dublin City University Research Ethics DCUREC/2018/246. A manuscript of the results will be submitted to a peer-reviewed journal and results will be presented at conferences, community and consumer forums and hospital research conferences. TRIAL REGISTRATION NUMBER: ISRCTN83783446; Pre-results.

Indexed as

Hypertension, PulmonaryQuality of LifeActivities of Daily LivingClinical Trials as TopicExercise TherapyFeasibility StudiesHumansrehabilitation medicinerespiratory physiologysports medicine

Identifiers

PMID33972341
PMCPMC8112432
OpenAlexW3162768167

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.