ArticlebioRxiv : the preprint server for biology2021
ORAI1 establishes resistance to SARS-CoV-2 infection by regulating tonic type I interferon signaling.
Beibei Wu, Arunachalam Ramaiah, Gustavo Garcia, Yousang Gwack, Vaithilingaraja Arumugaswami, Sonal Srikanth
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 9 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors at 3 institutions in 2 countries.
Beibei Wu *Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Arunachalam Ramaiah *Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697, USA.
Gustavo GarciaDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Yousang GwackDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Vaithilingaraja ArumugaswamiDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Sonal SrikanthDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
University of California, Los Angeles · USCalifornia NanoSystems Institute · USUniversity of California, Irvine · US
Funding
Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5MVirology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KITCHEN, SCOTT G · 1991 to 2018
$39.9MNovel regulators of store-operated Ca2+ entry in immune systemsR01AI083432 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG · 2009 to 2020
$3.8MInterplay between AMPK and Hippo Signaling Regulates Ocular Antiviral Response to Zika virus infectionR01EY032149 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Vaithilingaraja Arumugaswami, Ashok Kumar · 2021 to 2026
$2.8MMechanism underlying regulation of Ca2+ signaling in local effector T cellsR01AI146615 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG · 2020 to 2024
$1.8MRegulation of the STING pathway under sterile conditionsR01AI146352 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SRIKANTH, SONAL · 2020 to 2023
$1.6MDistinctive role of ORAI3 channels in the effector T cell responseR21AI149236 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG · 2020 to 2021
$429kRole of Orai1 trafficking in local effector T cell responsesR56AI146615 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG · 2019 to 2019
$390kDevelopment of an animal model of severe neutrophilic asthmaR03AI147063 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GWACK, YOUSANG · 2019 to 2020
$156kNCI NIH HHS P30 CA016042NEI NIH HHS R01 EY032149NIAID NIH HHS P30 AI028697NIAID NIH HHS R01 AI083432NIAID NIH HHS R01 AI146352NIAID NIH HHS R01 AI146615NIAID NIH HHS R03 AI147063NIAID NIH HHS R21 AI149236NIAID NIH HHS R56 AI146615
6 · The paper itselfAbstract
ORAI1 and STIM1 are the critical mediators of store-operated Ca
Identifiers
PMID33972946
PMCPMC8109209
OpenAlexW3159198307
What Socratic holds
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