Evidence map›Paper›PMID 33986961›Full record

ArticleInternational journal of nephrology2021

CX3CR1 at V249M and T280M Gene Polymorphism and Its Potential Risk for End-Stage Renal Diseases in Egyptian Patients.

Asmaa Fathelbab Ibrahim, Asmaa Osama Bakr Seddik Osman, Lamiaa M Elabbasy, Mostafa Abdelsalam, A M Wahab, Maysaa El Sayed Zaki, Radwa Ahmed Rabea Abdel-Latif

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. The CX3CL1-CX3CR1 axis in HIV-associated inflammation and cardiometabolic disease.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Asmaa Fathelbab IbrahimLecturer of Clinical & Chemical Pathology, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt.ORCID https://orcid.org/0000-0002-5873-2613
Asmaa Osama Bakr Seddik OsmanClinical Pathology Department, Faculty of Medicine, Assiut University, Asyut, Egypt.ORCID https://orcid.org/0000-0001-6353-6118
Lamiaa M ElabbasyDepartment of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID https://orcid.org/0000-0003-1505-5357
Mostafa AbdelsalamMansoura Nephrology and Dialysis Unit, Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID https://orcid.org/0000-0002-4682-2777
A M WahabMansoura Nephrology and Dialysis Unit, Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID https://orcid.org/0000-0002-9873-0356
Maysaa El Sayed ZakiClinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID https://orcid.org/0000-0001-5431-0248
Radwa Ahmed Rabea Abdel-LatifLecturer of Clinical & Chemical Pathology, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt.ORCID https://orcid.org/0000-0002-2073-6555
Mansoura University · EGBeni-Suef University · EGAlfaisal University · SAAssiut University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CX3CL1-CX3CR1 pathway may be one of the future treatment targets to delay the progression of end-stage renal diseases. This study aimed to evaluate the CX3CR gene polymorphism in Egyptian patients with ESRD and its relation to fractalkine blood level. The study included 100 patients with ESRD on dialysis, 61 males and 39 females with mean age 51.02 ± 7.8 years. The V2491 genotype revealed a significant increase in the frequency of GG genotype in healthy control (83%) compared to patients [69%] with a significant increase in GA in patients [30%] compared to control subjects [15%],

Identifiers

PMID33986961
PMCPMC8093072
OpenAlexW3157514748

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.