Evidence map›Paper›PMID 33987145›Full record

ArticleCanadian journal of gastroenterology & hepatology2021

Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma.

Farshid Fathi, Behnam Sanei, Mazdak Ganjalikhani Hakemi, Reza F Saidi, Abbas Rezaei

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  8. Frontiers in microbiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Farshid FathiDepartment of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0002-0280-7612
Behnam SaneiDepartment of Hepatobiliary & Pancreatic Surgery and Liver Transplantation, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0003-4393-7832
Mazdak Ganjalikhani HakemiDepartment of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0002-4764-7616
Reza F SaidiDivision of Transplant Services, Department of Surgery, SUNY Upstate Medical University Syracuse, Syracuse, NY 13210, USA.ORCID 0000-0002-7389-2981
Abbas RezaeiDepartment of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0003-0758-6844
Isfahan University of Medical Sciences · IRSUNY Upstate Medical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. This study investigated how the expressions and serum levels of some pro- and anti-inflammatory cytokines in patients with hepatocellular carcinoma (HCC) were changed during LR. Methods: Liver tissues from 15 patients with HCC were collected and the levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF- Results: After 60 and 90 minutes of LR, IL-6 gene expression was significantly increased ( Conclusion: Our data provided further evidence to reveal that IL-6 and TNF-

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsCytokinesHumansTumor Necrosis Factor-alphaCytokinesTumor Necrosis Factor-alpha

Identifiers

PMID33987145
PMCPMC8093046
OpenAlexW3149691249

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.