Evidence map›Paper›PMID 33991129›Full record

ArticleJournal of veterinary internal medicine2021

Accuracy of a flash glucose monitoring system in cats and determination of the time lag between blood glucose and interstitial glucose concentrations.

Francesca Del Baldo, Federico Fracassi, Jully Pires, Antonio Maria Tardo, Eleonora Malerba, Elisa Manassero, Chen Gilor

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  3. Spectrum of veterinary care in feline diabetes mellitus.Journal of feline medicine and surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Francesca Del BaldoDepartment of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, Italy.
Federico FracassiDepartment of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, Italy.ORCID https://orcid.org/0000-0003-3121-2199
Jully PiresDepartment of Veterinary Medicine and Epidemiology University of California Davis, Davis, California, USA.
Antonio Maria TardoDepartment of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, Italy.
Eleonora MalerbaDepartment of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, Italy.
Elisa ManasseroClinica Albese per Animali da Compagnia, Cuneo, Italy.
Chen GilorDepartment of Veterinary Medicine and Epidemiology University of California Davis, Davis, California, USA.ORCID https://orcid.org/0000-0003-0393-4135
University of Bologna · ITCentro Ricerche Produzioni Animali · ITUniversity of California, Davis · USUniversity of Florida · US

Funding

Established Investigator Award from the European College of Veterinary Internal Medicine Clinical Studies Fund
6 · The paper itself

Abstract

backgroundThe FreeStyle Libre (Abbott Laboratories) is a flash glucose monitoring system (FGMS) that measures interstitial glucose concentration (IG). The system is factory-calibrated, easy to use, inexpensive, and could be useful for monitoring diabetic cats.

objectivesTo evaluate the analytical and clinical accuracy of the FGMS in cats and establish the lag-time between IG and blood glucose concentration (BG). ANIMALS: Twenty client-owned diabetic cats and 7 purpose-bred healthy cats.

methodsProspective study. Blood glucose concentration was measured using a portable glucose meter validated for use in cats that served as a reference method for IG, as measured by FGMS. In diabetic cats, data were collected for sensor wearing time with different methods of application and accuracy across glycemic ranges. Accuracy was determined by fulfillment of ISO15197:2013 criteria. In healthy cats, lag-time between IG and BG was established after IV administration of exogenous glucose.

resultsGood agreement between IG and BG was obtained (r = .93). Analytical accuracy was not achieved, whereas clinical accuracy was demonstrated with 100% of the results in zones A + B of the Parkes consensus error grid analysis. In the immediate 30 minutes after an IV bolus of glucose, when BG was increasing rapidly (approximately 2%/min), IG increased slowly, resulting in a difference of as much as 579 mg/dL, and no positive correlation between BG and IG was found. CONCLUSIONS AND CLINICAL IMPORTANCE: The FGMS did not fulfill ISO requirements but is sufficiently accurate for glucose monitoring in cats, while considering the lag between IG and BG during periods of rapid changes in BG.

Indexed as

Cat DiseasesDiabetes MellitusAnimalsBlood GlucoseBlood Glucose Self-MonitoringCatsInjections, IntravenousProspective StudiesBlood Glucosecontinuous glucose monitoring systemdelaydiabetes mellitusFreeStyle Libreinsulin

Identifiers

PMID33991129
PMCPMC8163110
OpenAlexW3163601230

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.