SynthesisFrontiers in nutrition2021
A Systematic Review of Obesity and Binge Eating Associated Impairment of the Cognitive Inhibition System.
Synthesis in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Loss of Control over Eating, Inhibitory Control, and Reward Sensitivity in Children and Adolescents: A Systematic Review.Nutrients · 2023Pooled it
- Tirzepatide on ingestive behavior in adults with overweight or obesity: a randomized 6-week phase 1 trial.Nature medicine · 2025Trial
- Prefrontal oxygenation during verbal fluency in severe obesity.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Screen Time, Unhealthy Eating Behaviors, and Associated Health Risks in Children: A Narrative Review.Children (Basel, Switzerland) · 2026Review
- How does body mass influence inhibitory control? Event-related potentials evidence across the full BMI spectrum.Experimental brain research · 2026Article
- Neurocognitive performance and appetite-regulating hormones in obesity with and without eating disorders: A comprehensive review and empirical analysis.Reviews in endocrine & metabolic disorders · 2026Review
- Machine learning-based identification of abnormal functional connectivity in obesity across different metabolic states.Communications medicine · 2026Article
- A feasibility study of the effects of concurrent transcranial direct current stimulation (tDCS) on mindfulness training in adults living with overweight or obesity: the MINDED trial protocol.Pilot and feasibility studies · 2026Article
- Multimodal machine learning reveals neurobiological signatures of binge-type eating disorders.Frontiers in neuroscience · 2026Article
- Sex and age effects on binge eating spectrum disorders in young adults: a path analysis.Frontiers in psychology · 2026Article
- Intermittent theta burst stimulation (iTBS) and inhibitory control training to reduce binge eating: study protocol for a randomized controlled trial (Be-Nemoic).Frontiers in psychology · 2026Article
- Functional connectome fingerprinting related to BMI and its association with impulsivity.Brain imaging and behavior · 2025Article
- Impact of Obesity on Appetite-Related Behaviors and Biomarkers in Older Adults: A Cross-Sectional Study.Obesity science & practice · 2025Article
- Delay discounting and nucleus accumbens functional connectivity are related to weight status in adolescents from the ABCD study.Pediatric obesity · 2025Article
- Self-rated health habits, mental health, emotional intelligence, and impulsivity across the Baltic States.Frontiers in public health · 2025Article
- The best exercises from top 20 by health-related indicators.Frontiers in public health · 2025Article
- Enhancing the outcomes of bariatric surgery with inhibitory control training, electrical brain stimulation and psychosocial aftercare: a pilot study protocol.Journal of eating disorders · 2024Article
- Reward and Inhibitory Control as Mechanisms and Treatment Targets for Binge Eating Disorder.Current psychiatry reports · 2024Review
- The role of impulsivity and binge eating in outpatients with overweight or obesity: an EEG temporal discounting study.Journal of eating disorders · 2024Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Altered functioning of the inhibition system and the resulting higher impulsivity are known to play a major role in overeating. Considering the great impact of disinhibited eating behavior on obesity onset and maintenance, this systematic review of the literature aims at identifying to what extent the brain inhibitory networks are impaired in individuals with obesity. It also aims at examining whether the presence of binge eating disorder leads to similar although steeper neural deterioration. We identified 12 studies that specifically assessed impulsivity during neuroimaging. We found a significant alteration of neural circuits primarily involving the frontal and limbic regions. Functional activity results show BMI-dependent hypoactivity of frontal regions during cognitive inhibition and either increased or decreased patterns of activity in several other brain regions, according to their respective role in inhibition processes. The presence of binge eating disorder results in further aggravation of those neural alterations. Connectivity results mainly report strengthened connectivity patterns across frontal, parietal, and limbic networks. Neuroimaging studies suggest significant impairment of various neural circuits involved in inhibition processes in individuals with obesity. The elaboration of accurate therapeutic neurocognitive interventions, however, requires further investigations, for a deeper identification and understanding of obesity-related alterations of the inhibition brain system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.