Evidence map›Paper›PMID 33997162›Full record

ReviewGenes & diseases2021

Comprehensive biological function analysis of lncRNAs in hepatocellular carcinoma.

Dan Wang, Fengjiao Chen, Tao Zeng, Qingxia Tang, Bing Chen, Ling Chen, Yan Dong, Xiaosong Li

Abstract readReview
In one paragraph

Review in Genes & diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. TheAnnals of translational medicine · 2022
    Article
  9. Review
  10. Epigenetic remodelling in human hepatocellular carcinoma.Journal of experimental & clinical cancer research : CR · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dan WangDepartment of Clinical Laboratory, People's Hospital of Rongchang District, Chongqing, Rongchang 402460, PR China.
Fengjiao ChenKey Laboratory of Molecular Biology of Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, 400016, PR China.
Tao ZengChengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Sichuan Province, Chengdu, 611731, PR China.
Qingxia TangDepartment of Clinical Laboratory, People's Hospital of Rongchang District, Chongqing, Rongchang 402460, PR China.
Bing ChenDepartment of Clinical Laboratory, People's Hospital of Rongchang District, Chongqing, Rongchang 402460, PR China.
Ling ChenKey Laboratory of Molecular Biology of Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, 400016, PR China.
Yan DongClinical Molecular Medicine Testing Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, PR China.
Xiaosong LiClinical Molecular Medicine Testing Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thousands of long non-coding RNAs (lncRNAs) have been discovered in human genomes by gene chip, next-generation sequencing, and/or other methods in recent years, which represent a significant subset of the universal genes involved in a wide range of biological functions. An abnormal expression of lncRNAs is associated with the growth, invasion, and metastasis of various types of human cancers, including hepatocellular carcinoma (HCC), which is an aggressive, highly malignant, and invasive tumor, and a poor prognosis in China. With a more in-depth understanding of lncRNA research for HCC and the emergence of new molecular-targeted therapies, the diagnosis, treatment, and prognosis of HCC will be considerably improved. Therefore, this review is expected to provide recommendations and directions for future lncRNA research for HCC.

Indexed as

AASLD, American Association for the Study of Liver DiseasesceRNAsceRNAs, Competing endogenous RNAsHCCHCC, Hepatocellular carcinomalncRNAslncRNAs, Long non-coding RNAsmiRNAsmiRNAs, microRNAsmRNA, Messenger RNAncRNAsncRNAs, Non-coding RNAsRNA, Ribonucleic acidsnoRNAssnoRNAs, Small nucleolar RNAs

Identifiers

PMID33997162
PMCPMC8099694

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.