Evidence map›Paper›PMID 33997428›Full record

ArticleHeliyon2021

High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand.

Aroon La-Up, Udomsak Saengow, Apinun Aramrattana

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. The effects of kratomFrontiers in pharmacology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Clinical Implications of Kratom (Current addiction reports · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Aroon La-UpSchool of Public Health, Walailak University, 222 Thai Buri, Tha Sala, Nakhon Si Thammarat 80160, Thailand.
Udomsak SaengowSchool of Medicine, Walailak University, 222 Thai Buri, Tha Sala, Nakhon Si Thammarat 80160, Thailand.
Apinun AramrattanaFaculty of Medicine, Department of Family Medicine, Chiang Mai University, Chiang Mai, Thailand.
Walailak University · THChiang Mai University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study aims to examine the association between Kratom use and serum lipid level.

methodThis study compared the serum lipid profile of Kratom users and non-users living in Nam Phu Subdistrict, a special area that allows the traditional use of Kratom. The study subjects consisted of 581 individuals aged 18 and above. Binary logistic regression was used to determine an association between Kratom use and serum lipid level.

resultsThe findings revealed an association between Kratom use and an elevated HDL level (≥60 mg/dL) with an adjusted OR of 1.82 (95% CI, 1.17-2.8), and an association between Kratom use and a triglyceride level <90 mg/dL with an adjusted OR of 1.75 (95% CI; 1.17-2.63). There were no associations between Kratom use and LDL as well as total cholesterol level. DISCUSSION AND

conclusionsThis study provided additional evidence of Kratom use and a favorable lipid profile. Prevention of coronary heart disease or cerebrovascular disease via an improvement in the lipid profile may be a future pharmaceutical application of Kratom.

Indexed as

HDLKratomMitragyna speciosaSerum lipidtriglyceride

Identifiers

PMID33997428
PMCPMC8102425
OpenAlexW3158475209

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.