Evidence map›Paper›PMID 33998871›Full record

ArticleCannabis and cannabinoid research2021

Effect of Cannabidiol on the Long-Term Toxicity and Lifespan in the Preclinical Model

M Hunter Land, Marton L Toth, Laura MacNair, Siva A Vanapalli, Timothy W Lefever, Erica N Peters, Marcel O Bonn-Miller

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Cannabis and cannabinoid research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06362889 (An Exploratory Study to Evaluate the Safety and Efficacy of Microneedling With Cannabidiol), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06362889 phase1not yet recruitingnot on this mapstarted 2025, after this paper: background citation

An Exploratory Study to Evaluate the Safety and Efficacy of Microneedling With Cannabidiol (CBD) and Hempseed Oil for Treating Acne Vulgaris

TypeinterventionalSponsorRejuva Medical AestheticsRan2025 to 2025Enrolled20ConditionsAcne Vulgaris (Disorder)ArmsMicroneedling with CBD
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  8. Review
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  12. Article
  13. Review
  14. The Endocannabinoid System in Caenorhabditis elegans.Reviews of physiology, biochemistry and pharmacology · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Open veterinary journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

M Hunter LandCanopy Growth Corporation, Smiths Falls, Ontario, Canada.
Marton L TothNemaLife, Inc., Lubbock, Texas, USA.
Laura MacNairCanopy Growth Corporation, Smiths Falls, Ontario, Canada.
Siva A VanapalliNemaLife, Inc., Lubbock, Texas, USA.
Timothy W LefeverCanopy Growth Corporation, Smiths Falls, Ontario, Canada.
Erica N PetersCanopy Growth Corporation, Smiths Falls, Ontario, Canada.
Marcel O Bonn-MillerCanopy Growth Corporation, Smiths Falls, Ontario, Canada.
III-N Technology (United States) · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CannabidiolThermotoleranceAnimalsCaenorhabditis elegansHumansLongevityCannabidiolagingcannabidiolhealthlifespanmotilitytoxicity

Identifiers

PMID33998871
PMCPMC8713279
OpenAlexW3107527175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.