Evidence map›Paper›PMID 33998879›Full record

ArticleCannabis and cannabinoid research2022

The Cannabinoid Receptor Agonist, WIN-55212-2, Suppresses the Activation of Proinflammatory Genes Induced by Interleukin 1 Beta in Human Astrocytes.

Jerel Adam Fields, Mary K Swinton, Patricia Montilla-Perez, Eugenia Ricciardelli, Francesca Telese

Open access · greenAbstract read
In one paragraph

Article in Cannabis and cannabinoid research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Review
  9. Long-Term Treatment with Cannabidiol-EnrichedInternational journal of molecular sciences · 2023
    Article
  10. Review
  11. Review
  12. Chronic adolescent exposure to cannabis in mice leads to sex-biased changes in gene expression networks across brain regions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jerel Adam FieldsDepartment of Psychiatry and University of California San Diego, La Jolla, California, USA.
Mary K SwintonDepartment of Psychiatry and University of California San Diego, La Jolla, California, USA.
Patricia Montilla-PerezDepartment of Medicine, University of California San Diego, La Jolla, California, USA.
Eugenia RicciardelliInstitute of Genomic Medicine, University of California San Diego, La Jolla, California, USA.
Francesca TeleseDepartment of Medicine, University of California San Diego, La Jolla, California, USA.
University of California San Diego · US

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jessica Lynette Montoya · 2001 to 2026
$50.4M
Decoding the grammar of transcriptional enhancers regulating different stages of opioid use disorderU01DA051972 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BENNER, CHRISTOPHER W, TELESE, FRANCESCA · 2020 to 2024
$3.4M
Epigenomic approaches to study the gene networks underlying the cannabis effects on genetic vulnerability to psychosisDP1DA042232 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TELESE, FRANCESCA · 2016 to 2020
$2.3M
The role of TFAM alterations in HIV- and ART-induced mitochondrial dysfunction in the brainR01MH128108 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jerel Adam Fields · 2022 to 2026
$2.3M
The role of TREM2 in Alzheimer's disease neuropathogenesis in HIV+ individualsR56AG066215 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELDS, JEREL ADAM · 2020 to 2020
$749k
Mitochondrial biogenesis dysfunction in the CNS of HIV-infected individuals on antiretroviral therapyK01MH115819 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELDS, JEREL ADAM · 2018 to 2020
$480k
NIA NIH HHS R56 AG066215NIDA NIH HHS DP1 DA042232NIDA NIH HHS U01 DA051972NIMHD NIH HHS L60 MD013161NIMH NIH HHS K01 MH115819NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH128108
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AstrocytesCannabinoid Receptor AgonistsAnimalsAnti-Inflammatory AgentsBenzoxazinesEndocannabinoidsHumansInflammationInterleukin-1betaMorpholinesNaphthalenesPeroxisome Proliferator-Activated Receptors(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanoneAnti-Inflammatory AgentsBenzoxazinesCannabinoid Receptor AgonistsEndocannabinoidsIL1B protein, humanInterleukin-1betaMorpholinesNaphthalenesPeroxisome Proliferator-Activated Receptorsimmunosuppressioninflammationneurobiologysynthetic cannabinoids

Identifiers

PMID33998879
PMCPMC8864424
OpenAlexW3120322611

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.