ArticleClinical interventions in aging2021
Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls.
Article in Clinical interventions in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Comorbidities in primary cicatricial alopecia: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Liver fibrosis prevalence and risk factors in patients with psoriasis: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Platelet-rich plasma in alopecia areata and primary cicatricial alopecias: A systematic review.Frontiers in medicine · 2022Pooled it
- Isolated Actinic Prurigo Cheilitis in an Elderly Thai Female: An Atypical Presentation.Clinical, cosmetic and investigational dermatology · 2026Article
- Porokeratotic Eccrine Ostial and Dermal Duct Nevus: A Report of Rare Late-Onset Solitary Lesion.Clinical, cosmetic and investigational dermatology · 2025Article
- The Disturbed Microbial Niches of Itchy Scalp.Journal of cosmetic dermatology · 2025Article
- Papular Acantholytic Dyskeratosis of the Vulva: A Case Report and Literature Review.Clinical, cosmetic and investigational dermatology · 2025Article
- Using the follicular unit extraction technique in treatment of male androgenetic alopecia.BMC surgery · 2024Article
- Causal Effects of Lipids-Related Metabolites on Androgenic Alopecia: A Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2024Article
- Late-Onset Eruptive Clear Cell Syringoma: A Case Report and Literature Review.Clinical, cosmetic and investigational dermatology · 2024Article
- Lichen Sclerosus of the Labial Mucosa: A Case Report and Literature Review.Clinical, cosmetic and investigational dermatology · 2024Article
- Latanoprost-Loaded Nanotransfersomes Designed for Scalp Administration Enhance Keratinocytes Proliferation.Molecular pharmaceutics · 2023Article
- Differences in Demographic and Clinical Characteristics Among Subtypes of Female Pattern Hair Loss.Clinical, cosmetic and investigational dermatology · 2023Article
- Trichoscopic Features of Syphilitic Alopecia and Alopecia Areata: A Comparative Study.Clinical, cosmetic and investigational dermatology · 2023Article
- Unrevealing the Potential ofMolecules (Basel, Switzerland) · 2022Article
- Microbiota profiling on itchy scalp with undetermined origin.Archives of microbiology · 2022Article
- Relative Efficacy of Minoxidil and the 5-α Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis.JAMA dermatology · 2022Article
- Comparative analysis of scalp and gut microbiome in androgenetic alopecia: A Korean cross-sectional study.Frontiers in microbiology · 2022Article
- Measuring Patient Quality of Life Following Treatment for Alopecia.Patient preference and adherence · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAndrogenetic alopecia (AGA) is the most common type of hair loss in men. Its prevalence increases with advancing age. Characteristics of hair loss in male AGA reveal the possibility of different biophysical and physiological profiles between androgen-sensitive (vertex) and androgen-insensitive (occipital) scalps. However, these variations have not been well investigated.
objectiveWe aimed to evaluate and compare scalp biophysical and physiological characteristics in male AGA patients and healthy controls.
methodsScalp biophysiological profiles were evaluated by non-invasive measuring techniques, including skin surface lipids (SSL), transepidermal water loss (TEWL), and stratum corneum hydration (SCH) on both vertex and occipital areas. Values were compared between scalp areas and study groups. Participants with AGA were further categorized based on disease severity (Hamilton-Norwood classification) for subgroup analyses. Correlation coefficients were evaluated to determine the effects of AGA severity and age on each functional parameter.
resultsParticipants were 31 AGA subjects and 31 healthy controls. The vertex scalp of AGA patients had significantly higher SSL (
conclusionMale AGA presents with different biophysical and physiological characteristics in androgen-sensitive and androgen-insensitive areas, and with further differences from controls. These findings could direct further research and aid in the development of optimal hair and scalp treatments to improve scalp functional profiles in particular patients.
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