Evidence map›Paper›PMID 34016161›Full record

ArticleMicrobiome2021

The impact of cross-kingdom molecular forensics on genetic privacy.

Eran Elhaik, Sofia Ahsanuddin, Jake M Robinson, Emily M Foster, Christopher E Mason

Abstract readLetterVideo-Audio Media
In one paragraph

Article in Microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Microbial genomics: a potential toolkit for forensic investigations.Forensic science, medicine, and pathology · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eran ElhaikDepartment of Biology, Lund University, 22362, Lund, Sweden. eran.elhaikj@biol.lu.se.ORCID 0000-0003-4795-1084
Sofia AhsanuddinDepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, USA.
Jake M RobinsonThe Department of Landscape Architecture, University of Sheffield, Sheffield, S10 2TN, UK.
Emily M Foster, Columbia, USA.
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10021, USA. chm2042@med.cornell.edu.

Funding

Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5M
Study of Neural Tube Defects Etiology: Genome and ExposomeR01ES021006 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI FINNELL, RICHARD H., MASON, CHRISTOPHER EDWARD · 2012 to 2014
$1.0M
Community Research Education and Engagement for Data Science (CREEDS)R25EB020393 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLAUDIO, LUZ, KOVATCH, PATRICIA · 2015 to 2017
$578k
Alfred P. Sloan Foundation G-2015-13964Bill and Melinda Gates Foundation OPP1151054Directorate for Biological Sciences 1120622Erik Philip-Sörensen Foundation G2020-011Foundation for the National Institutes of Health R25EB020393, R01AI125416, R01ES021006Kennedy Space Center NNX14AH50G, NNX17AB26GNASA NNX14AH50GNASA NNX17AB26GNIAID NIH HHS R01 AI125416NIBIB NIH HHS R25 EB020393NIEHS NIH HHS R01 ES021006Starr Cancer Consortium grants I9-A9-071Vetenskapsrådet 2020-03485
6 · The paper itself

Abstract

Recent advances in metagenomic technology and computational prediction may inadvertently weaken an individual's reasonable expectation of privacy. Through cross-kingdom genetic and metagenomic forensics, we can already predict at least a dozen human phenotypes with varying degrees of accuracy. There is also growing potential to detect a "molecular echo" of an individual's microbiome from cells deposited on public surfaces. At present, host genetic data from somatic or germ cells provide more reliable information than microbiome samples. However, the emerging ability to infer personal details from different microscopic biological materials left behind on surfaces requires in-depth ethical and legal scrutiny. There is potential to identify and track individuals, along with new, surreptitious means of genetic discrimination. This commentary underscores the need to update legal and policy frameworks for genetic privacy with additional considerations for the information that could be acquired from microbiome-derived data. The article also aims to stimulate ubiquitous discourse to ensure the protection of genetic rights and liberties in the post-genomic era. Video abstract.

Indexed as

Genetic PrivacyPrivacyGenomicsHumansMetagenomeMetagenomicsForensicsGenetic discriminationGenetic privacyGenomicsMetagenomicsMicrobiomicsNext-generation sequencing

Identifiers

PMID34016161
PMCPMC8138925

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.