SynthesisThe Journal of cardiovascular nursing
Frailty as a Predictor of Postoperative Outcomes in Invasive Cardiac Surgery: A Systematic Review of Literature.
Synthesis in The Journal of cardiovascular nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Impact of frailty on post-procedural adverse outcomes in older adults aged ≥75 years undergoing percutaneous coronary intervention: a systematic review of observational studies.Frontiers in medicine · 2026Pooled it
- Prevalence and risk factors of frailty among cardiac surgery patients: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Frailty Assessment and Its Impact in Hospital Outcomes After Cardiac Surgery - A Prospective Observational Study.Brazilian journal of cardiovascular surgery · 2026Observational
- Interventional treatment options for elderly patients with mitral regurgitation.Future cardiology · 2026Review
- Postoperative atrial fibrillation as an independent predictor of 90-day complications in geriatric patients undergoing coronary artery bypass grafting.Journal of geriatric cardiology : JGC · 2026Article
- Frailty and Severe White Matter Lesions Are Risk Factors for Surgical Treatment for Unruptured Cerebral Aneurysm in Older Adults.Neurologia medico-chirurgica · 2026Article
- Impact of Frailty Risk on Adverse Outcomes after Open Heart Valve Surgery in Older Patients: A Retrospective Cohort Study.Progress in rehabilitation medicine · 2026Article
- Frailty Risk After a Cardiovascular Event Among Community-Dwelling Older People: Influence of Sociodemographic, Polypharmacy, and Pre-event Frailty.The Canadian journal of cardiology · 2025Article
- Racial Differences in Length of Stay After Atrial Fibrillation Ablation.Pacing and clinical electrophysiology : PACE · 2025Article
- Mid-Term Mortality Prediction Using Four Established Risk Scores in Patients with Chronic Limb-Threatening Ischemia Undergoing Cardiac Surgery.Journal of clinical medicine · 2025Article
- Association between preoperative frailty and postoperative delirium and cognitive dysfunction in elderly patients undergoing surgery under general anaesthesia: A prospective observational study.Indian journal of anaesthesia · 2025Article
- The Prognostic Value of Frailty in a Transcatheter Mitral Valve-in-Valve Cohort.Structural heart : the journal of the Heart Team · 2025Article
- Which frailty score in cardiac surgery patients?Turk gogus kalp damar cerrahisi dergisi · 2025Article
- Start Strong, Finish Strong: A Review of Prehabilitation in Cardiac Surgery.Life (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesFrailty is a syndrome characterized by increased vulnerability and reduced ability to maintain homeostasis after stressful events that results in an increased risk for poor outcomes. Frailty screening could potentially be valuable in cardiac surgery risk assessment. The purpose of this review is to evaluate the current literature linking multicomponent frailty assessment and invasive cardiac surgery outcomes.
methodsWe searched PubMed, EMBASE, and CINAHL; 1887 articles met the search criteria, and each was independently reviewed by 2 reviewers.
resultsThe 19 eligible studies assessed 52 291 subjects using 17 different frailty measurements. The most commonly used instruments were the Fried Frailty Phenotype and the Clinical Frailty Scale. Between 9% and 61% of participants were found to be frail in each study. All 19 studies included mortality as an outcome, 12 included surgical complications, 12 included hospital length of stay, 3 included quality of life, and 2 included functional status. Nine found statistically significant differences in survival between frail and nonfrail patients, 6 of 12 found that frail patients had a longer length of stay, 4 of 12 found that frail patients were more likely to experience major complications, and 2 of 2 found that frail patients were more likely to have a decrease in functional status.
conclusionAlthough some studies lacked power, the majority confirmed that frail patients are more likely to experience poor outcomes. Further research is needed to determine which frailty measure provides the best predictive validity and to identify interventions to mitigate the risks that major cardiac surgery poses to frail patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.