Evidence map›Paper›PMID 34017573›Full record

ArticleAmerican journal of translational research2021

Monosialotetrahexosylganglioside sodium combined with hyperbaric oxygen on nervous system development and brain physiology in children with hypoxic ischemic encephalopathy.

Xiuli Wang, Yulin Chen, Yonghong Wang, Linbao Wen

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Hypoxic ischemic encephalopathy (HIE).Frontiers in neurology · 2024
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xiuli WangDepartment of Pediatrics, Liaocheng People's Hospital Liaocheng 252500, Shandong, China.
Yulin ChenDepartment of Surgical Anesthesiology, Tai'an City Central Hospital Tai'an 271000, Shandong, China.
Yonghong WangDepartment of Hepatobiliary Surgery, Tai'an City Central Hospital Tai'an 271000, Shandong, China.
Linbao WenDepartment of Neurosurgery, Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Guiyang 550001, Guizhou, China.
Taian City Central Hospital · CNAffiliated Hospital of Guizhou Medical University · CNLiaocheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the short-term and long-term clinical effects of monosialotetrahexosylganglioside sodium (GM1) combined with hyperbaric oxygen in neonatal hypoxic ischemic encephalopathy. A total of 80 children with hypoxic ischemic encephalopathy who were admitted to our hospital from January 2016 to March 2018 were selected and divided into the observation group and control group according to a random alphabet method, with 40 cases in each group. Neuron-specific enolase (NSE) and amplitude-integrated electroencephalogram (aEEG) were monitored after treatment in both groups, and the mental development index (MDI) and the psychomotor development index (PDI) of children were evaluated by the Bayley Scales of Infant Development (BSID) 12 months after discharge. The results showed that there were no significant differences in NSE levels and aEEG scores of children with mild severity between the two groups after treatment (

Indexed as

hyperbaric oxygenHypoxic ischemic encephalopathymonosialotetrahexosylganglioside sodiumnervous system development

Identifiers

PMID34017573
PMCPMC8129238
OpenAlexW3160141904

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.