Evidence map›Paper›PMID 34022935›Full record

ArticleParasites & vectors2021

High larvicidal efficacy of yeast-encapsulated orange oil against Aedes aegypti strains from Brazil.

Bruno Gomes, Huarlen Ogélio, Fabiane Brant, Camila Jesus Pereira-Pinto, Michael J Workman, Monique Costa, José Bento Pereira Lima, Ademir Jesus Martins, Marcelo Ramalho-Ortigao, Ravi Durvasula and 3 more

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Insecticidal Potential ofPlants (Basel, Switzerland) · 2025
    Article
  3. Larvicide activity of yeast-encapsulated orange oil againstCurrent research in parasitology & vector-borne diseases · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Bruno GomesLaboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil. gsilva.bruno@gmail.com.
Huarlen OgélioLaboratório de Mosquitos Transmissores de Hematozoários, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.
Fabiane BrantLaboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.
Camila Jesus Pereira-PintoLaboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.
Michael J WorkmanCenter for Global Health, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Monique CostaLaboratório de Fisiologia E Controle de Artrópodes Vetores, Oswaldo Cruz Institute - Oswaldo Cruz Foundation (IOC-FIOCRUZ), Rio de Janeiro, Brazil.
José Bento Pereira LimaLaboratório de Fisiologia E Controle de Artrópodes Vetores, Oswaldo Cruz Institute - Oswaldo Cruz Foundation (IOC-FIOCRUZ), Rio de Janeiro, Brazil.
Ademir Jesus MartinsLaboratório de Fisiologia E Controle de Artrópodes Vetores, Oswaldo Cruz Institute - Oswaldo Cruz Foundation (IOC-FIOCRUZ), Rio de Janeiro, Brazil.
Marcelo Ramalho-OrtigaoDepartment of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD, USA.
Ravi DurvasulaLoyola University Stritch School of Medicine, Maywood, IL, USA.
Ivy HurwitzCenter for Global Health, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Mariana Rocha David *Laboratório de Mosquitos Transmissores de Hematozoários, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.
Fernando Ariel Genta *Laboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil. gentafernando@gmail.com.ORCID http://orcid.org/0000-0001-9558-1116
Fundação Oswaldo Cruz · BRInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular · BRUniversity of New Mexico · USLoyola University Chicago · USUniformed Services University of the Health Sciences · US

Funding

CDC HHS #200-2017-93140
6 · The paper itself

Abstract

backgroundBotanical substances such as essential oils (EOs) have demonstrated insecticidal properties and are a valid option for vector control. However, free EOs are unreliable as mosquito larvicides due their easy degradation by environmental exposure to ultraviolet light and higher temperatures. Here, we assessed the efficacy of a mosquito larvicide based on orange oil in a yeast-based delivery system against Aedes aegypti strains with different resistance status towards chemical neurotoxic insecticides. This larvicide preparation was physicochemically characterized in a previous report.

methodsLarvae of four Ae. aegypti strains from different regions of Brazil and different resistance profiles for deltamethrin (pyrethroid) and temephos (organophosphate) were tested against yeast-encapsulated orange oil (YEOO) in laboratory conditions for measurement of LC

resultsYEOO was found to be a highly active larvicide (LC

conclusionYEOO demonstrates high larvicidal activity against Ae. aegypti strains with resistant phenotypes for deltamethrin (PY) and temephos (OP). This larvicidal activity suggests the potential for the development of YEOO as an alternative intervention to synthetic insecticides in integrated vector management programs, for populations with resistance to commonly used insecticides.

Indexed as

AedesAnimalsBrazilInsecticidesLarvaMosquito ControlOils, VolatilePlant OilsPyrethrinsSaccharomyces cerevisiaeTemefosInsecticidesOils, Volatileorange oilPlant OilsPyrethrinsTemefosAedes aegyptiArbovirusCitrus sinensisDengueMosquito control

Identifiers

PMID34022935
PMCPMC8140510
OpenAlexW3165153875

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.