Evidence map›Paper›PMID 34024841›Full record

Observational studyJournal of Alzheimer's disease : JAD2021

Associations Between Neighborhood Park Access and Longitudinal Change in Cognition in Older Adults: The Multi-Ethnic Study of Atherosclerosis.

Lilah M Besser, Lun-Ching Chang, Kelly R Evenson, Jana A Hirsch, Yvonne L Michael, James E Galvin, Stephen R Rapp, Annette L Fitzpatrick, Susan R Heckbert, Joel D Kaufman and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Urban greenspace and dementia: Measures, mechanisms, and methodological guidance.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Rural Roads to Cognitive Resilience (RRR): A prospective cohort study protocol.medRxiv : the preprint server for health sciences · 2024
    Article
  16. Article
  17. Invited Perspective: Blue Skies and Alzheimer's Disease.Environmental health perspectives · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lilah M BesserInstitute for Human Health and Disease Intervention (I-HEALTH), Department of Urban and Regional Planning, Florida Atlantic University, Boca Raton, FL, USA.
Lun-Ching ChangDepartment of Mathematical Sciences, Florida Atlantic University, Boca Raton, FL, USA.
Kelly R EvensonDepartment of Epidemiology, Gillings School of Global Public Health, University of NC-Chapel Hill, Chapel Hill, NC, USA.
Jana A HirschUrban Health Collaborative and Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA.
Yvonne L MichaelUrban Health Collaborative and Department of Epidemiology and Biostatistics, Dornslife School of Public Health, Drexel University, Philadelphia, PA, USA.
James E GalvinComprehensive Center for Brain Health, Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Stephen R RappDepartment of Psychiatry & Behavioral Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Annette L FitzpatrickDepartments of Family Medicine, Epidemiology, and Global Health, University of Washington, Seattle, WA, USA.
Susan R HeckbertCardiovascular Health Research Unit and Department of Epidemiology, University of Washington, Seattle, WA, USA.
Joel D KaufmanDepartments of Environmental and Occupational Health Sciences, Medicine, and Epidemiology, University of Washington, Seattle, WA, USA.
Timothy M HughesDepartments of Internal Medicine and Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Funding

PREVENTABLE Vanguard PhaseU19AG065188 · NIA · DUKE UNIVERSITY · PI KAREN P ALEXANDER, WALTER T AMBROSIUS · 2019 to 2026
$96.2M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)R01AG058969 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Timothy M. Hughes, YONGMEI LIU · 2018 to 2026
$33.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Task Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2M
RAPID ACCELERATION OF DIAGNOTICS (RADX) ADVANCED TECHNOLOGIES PLATFORM RAPID ACCELERATION OF DIAGNOTICS (RADX) ADVANCED TECHNOLOGIES PLATFORM PROJECT75N92020C00006 · NHLBI · HELIX · PI LU, JAMES · 2021 to 2022
$12.5M
Wake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RAPP, STEPHEN R · 2016 to 2020
$12.2M
The SPRINT Alzheimer's, Seniors and Kidney Study (SPRINT ASK)R01AG055606 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI REBOUSSIN, DAVID M, WILLIAMSON, JEFF DOUGLAS · 2017 to 2023
$9.9M
Long-term impact of random assignment to intensive lifestyle intervention on Alzheimers disease and related dementias: The Action for Health in Diabetes ADRD Study (Look AHEAD-MIND)R01AG058571 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ESPELAND, MARK ANDREW, HAYDEN, KATHLEEN M · 2018 to 2021
$8.4M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NHLBI NIH HHS 75N92020C00006NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL071759NHLBI NIH HHS R01 HL127659NHLBI NIH HHS R01 HL131610NHLBI NIH HHS R01 HL133684NHLBI NIH HHS U01 HL096812NIA NIH HHS HHSN271201100004CNIA NIH HHS K01 AG063895NIA NIH HHS P30 AG049638NIA NIH HHS R01 AG040211NIA NIH HHS R01 AG049970NIA NIH HHS R01 AG050657NIA NIH HHS R01 AG053938NIA NIH HHS R01 AG054069NIA NIH HHS R01 AG054491NIA NIH HHS R01 AG055606NIA NIH HHS R01 AG058571NIA NIH HHS R01 AG058969NIA NIH HHS R03 AG064569NIA NIH HHS RF1 AG057033NIA NIH HHS U19 AG065188NIEHS NIH HHS P30 ES007033NINDS NIH HHS R01 NS101483NINDS NIH HHS RF1 NS110043
6 · The paper itself

Abstract

backgroundPreliminary evidence suggests associations between neighborhood park access and better late-life cognition and reduced Alzheimer's disease (AD) risk.

objectiveExamine associations between neighborhood park access and longitudinal change in cognition among U.S. older adults without dementia.

methodsWe used 2000-2018 observational data from the population-based, multi-site Multi-Ethnic Study of Atherosclerosis (n = 1,733). Measures included proportion of neighborhood park space (park access), distance to nearest park, and 6-year dichotomous and continuous change in scores on the Cognitive Abilities Screening Instrument (CASI; global cognition) and Digit Symbol Coding task (processing speed). Multivariable random intercept models tested main associations and mediation by depressive symptoms, physical activity, and PM2.5 exposure. Effect modification by race (African Americans/Blacks versus Whites) was tested using interaction terms.

resultsGreater park access (equivalent to 10%more in 1/2-mile around home) was associated with maintained/improved CASI score over six years independent of several covariates including individual- and neighborhood-level socioeconomic status (Odds ratio: 1.04; 95%confidence interval: 1.00-1.08). No other associations were observed with the dichotomous or continuous measures of cognitive change and no mediators were found. While a borderline association was seen between greater park access and maintained/improved CASI for African Americans/Blacks but not for Whites, effect modification was not confirmed by testing interaction terms.

conclusionNeighborhood park access may help maintain/improve late-life global cognition. However, our findings need replication in other population-based studies and regions. Additionally, studies are needed to determine if associations between park access and change in cognition vary by race/ethnicity to inform intervention efforts.

Indexed as

Parks, RecreationalResidence CharacteristicsAgedCognitionEthnicityExerciseFemaleHumansLongitudinal StudiesMaleUnited StatesAgingAlzheimer’s diseasecognitionenvironmentepidemiologylifestyleresidence characteristics

Identifiers

PMID34024841
PMCPMC8579707

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.