Evidence map›Paper›PMID 34030638›Full record

Trial reportBMC gastroenterology2021

Consumption of OLL1073R-1 yogurt improves psychological quality of life in women healthcare workers: secondary analysis of a randomized controlled trial.

Tetsu Kinoshita, Koutatsu Maruyama, Keiko Suyama, Mariko Nishijima, Kimiko Akamatsu, Akiko Jogamoto, Kikumi Katakami, Isao Saito

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Food science & nutrition · 2026
    Review
  7. Total dairy consumption is associated with healthy sleep patterns in U.S. adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tetsu KinoshitaSpecial Course of Food and Health Science, Department of Bioscience Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan. tetsu.prospective@gmail.com.
Koutatsu MaruyamaSpecial Course of Food and Health Science, Department of Bioscience Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan.
Keiko SuyamaDepartment of Community Health System Nursing, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Mariko NishijimaDepartment of Community Health System Nursing, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Kimiko AkamatsuDepartment of Fundamental and Clinical Nursing, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Akiko JogamotoDepartment of Fundamental and Clinical Nursing, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Kikumi KatakamiDepartment of Fundamental and Clinical Nursing, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Isao SaitoDepartment of Public Health and Epidemiology, Faculty of Medicine, Oita University, Yufu, Japan.
Ehime University · JPOita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe conducted a randomized controlled trial to investigate the effects of consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 in women healthcare workers. In a previous study we used these data to investigate hypothesized preventive effects against flu, however any effects on improving mental quality of life were not analyzed at that time. In the present study, we focus on that aspect.

methodsThe participants (961 women; mainly nurses, aged 20-71 years) were randomly allocated to either the yogurt group (n = 479) or the control group (n = 482). Participants in the yogurt group drank 112 mL of OLL1073R-1 yogurt for 16 weeks, while those in the control group did not consume any yogurt. All participants were prohibited from consuming other yogurt or fermented dairy products during the study period. The participants answered the Pittsburgh Sleep Quality Index (PSQI), Short Form-8 Health Survey (SF-8), and Gastrointestinal Symptom Rating Scale (GSRS) questionnaires at baseline and after 16 weeks.

resultsThe PSQI score showed significant improvement after the intake of yogurt (p < 0.01). SF-8 results showed significant intervention effects in the General Health and Vitality scores (p = 0.02 and p = 0.01, respectively). In other subscales of SF-8, we did not observe significant effects of the yogurt. In the GSRS, daily intake of yogurt exerted a preventive effect on constipation (p = 0.03).

conclusionsConsumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 enhances subjective psychological quality of life by improving quality of sleep and gastrointestinal condition among women healthcare workers.

Indexed as

Lactobacillus delbrueckiiQuality of LifeAdultAgedFemaleHealth PersonnelHumansMiddle AgedSurveys and QuestionnairesYogurtYoung AdultLactobacillus delbrueckii ssp. bulgaricus OLL1073R-1Psychological quality of lifeQuality of sleepWoman’s healthYogurt

Identifiers

PMID34030638
PMCPMC8142513
OpenAlexW3164117037

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.