ArticleNeurology2021
Association of SUMOylation Pathway Genes With Stroke in a Genome-Wide Association Study in India.
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Article in Neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Advances in genetics and multi-omics for ischemic stroke: from pathogenesis to clinical translation.Frontiers in genetics · 2026Review
- Short report: Targeted analysis of whole exome sequencing data in Indian cryptogenic stroke patients.PloS one · 2026Article
- Decoding Stroke Etiology: Multi-Omics Advancements in Genetic Mechanisms and Clinical Implication.Brain and behavior · 2025Review
- Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke.Stroke · 2024Article
- Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation via Hexosamine Biosynthetic Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Article
- Disease clusters subsequent to anxiety and stress-related disorders and their genetic determinants.Nature communications · 2024Article
- Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway.bioRxiv : the preprint server for biology · 2023Article
- Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries.Cell genomics · 2023Article
- Whole-exome sequencing analyses in a Saudi Ischemic Stroke Cohort reveal association signals, and shows polygenic risk scores are related to Modified Rankin Scale Risk.Functional & integrative genomics · 2023Article
- Influence of ZFHX3 Polymorphisms on the Risk of Ischemic Stroke in Chinese Han Population.Cardiovascular toxicology · 2023Article
- Common Genetic Factors and Pathways in Alzheimer's Disease and Ischemic Stroke: Evidences from GWAS.Genes · 2023Review
- Tat-NTS peptide protects neurons against cerebral ischemia-reperfusion injury via ANXA1 SUMOylation in microglia.Theranostics · 2023Article
- Grand challenges in stroke genomics.Frontiers in stroke · 2022Article
- Impact of RSUME Actions on Biomolecular Modifications in Physio-Pathological Processes.Frontiers in endocrinology · 2022Review
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24 authors at 1 institution in 1 country.
Amit KumarFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Ganesh ChauhanFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Shriram SharmaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Surekha DablaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
P N SylajaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Neera ChaudharyFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Salil GuptaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Chandra Sekhar AgrawalFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Kuljeet Singh AnandFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Achal Kumar SrivastavaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.ORCID 0000-0002-4590-7947
Deepti VibhaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.ORCID 0000-0003-3659-7526
Ram SagarFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Ritesh RajFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Ankita MaheshwariFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Subbiah VivekanandhanFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Bhavna KaulFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Samudrala RaghavanFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Sankar Prasad GorthiFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Dheeraj MohaniaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Samander KaushikFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Rohtas Kanwar YadavFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Anjali HazarikaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Pankaj SharmaFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India.
Kameshwar PrasadFrom the Department of Neurology (A.K., A.K.S., D.V., R.S., R.R., A.M., K.P.), Department of Neurobiochemisty (S.V.), Dr. R. P. Centre for Ophthalmic Sciences (D.M.), and Cardio-Neuro Centre (A.H.), All India Institute of Medical Sciences, New Delhi; Centre for Brain Research (G.C.), Indian Institute of Science, Bangalore; Department of Neurology (S.S.), North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya; Department of Neurology (S.D.), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana; Department of Neurology (P.N.S.), Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala; Department of Neurology (N.C., B.K., S.R.), Vardhman Mahavir Medical College and Safdarjung Hospital; Department of Neurology (S.G., S.P.G.), Army Research and Referral Hospital; Department of Neurology (C.S.A.), Sir Ganga Ram Hospital; Ram Manohar Lohia Hospital (K.S.A.); Department of Biotechnology (S.K.), Maharshi Dayanand University, Government of India, New Delhi; Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (R.K.Y.), Rohtak, Haryana, India; and Institute of Cardiovascular Research Royal Holloway (P.S.), University of London, Imperial College London, UK. Amit Kumar, Kameshwar Prasad, and Ganesh Chauhan are currently at Rajendra Institute of Medical Sciences, Ranchi, India. drkameshwarprasad@gmail.com.
All India Institute of Medical Sciences · IN
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo undertake a genome-wide association study (GWAS) to identify genetic variants for stroke in an Indian population.
methodsIn a hospital-based case-control study, 8 teaching hospitals in India recruited 4,088 participants, including 1,609 stroke cases. Imputed genetic variants were tested for association with stroke subtypes using both single-marker and gene-based tests. Association with vascular risk factors was performed with logistic regression. Various databases were searched for replication, functional annotation, and association with related traits. Status of candidate genes previously reported in the Indian population was also checked.
resultsAssociations of vascular risk factors with stroke were similar to previous reports and show modifiable risk factors such as hypertension, smoking, and alcohol consumption as having the highest effect. Single-marker-based association revealed 2 loci for cardioembolic stroke (1p21 and 16q24), 2 for small vessel disease stroke (3p26 and 16p13), and 4 for hemorrhagic stroke (3q24, 5q33, 6q13, and 19q13) at
conclusionsThis GWAS of stroke in an Indian population identified novel loci and replicated previously known loci. Genetic variants in the SUMOylation pathway, which has been implicated in brain ischemia, were identified for association with stroke.
Indexed as
Genetic Predisposition to DiseasePolymorphism, Single NucleotideAdultAgedAllelesBrain IschemiaCase-Control StudiesFemaleGenome-Wide Association StudyHumansIndiaMaleMiddle AgedPhenotypeQuantitative Trait LociRisk Factors
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.