Evidence map›Paper›PMID 34035808›Full record

ArticleInternational journal of endocrinology2021

Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD).

Tomasz Sawczyn, Dominika Stygar, Katarzyna Nabrdalik, Michał Kukla, Oliwia Masri, Łukasz Magrowski, Wojciech Karcz, Jerzy Jochem

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Tomasz SawczynDepartment of Physiology, Faculty of Medical Sciences, Zabrze, Medical University of Silesia, Katowice, Poland.ORCID https://orcid.org/0000-0001-8088-7681
Dominika StygarDepartment of Physiology, Faculty of Medical Sciences, Zabrze, Medical University of Silesia, Katowice, Poland.ORCID https://orcid.org/0000-0001-8509-7507
Katarzyna NabrdalikDepartment of Internal Medicine, Diabetology and Nephrology, Zabrze, Medical University of Silesia, Katowice, Poland.ORCID https://orcid.org/0000-0002-0777-8048
Michał KuklaDepartment of Internal Medicine and Geriatrics, Jagiellonian University Medical College, Krakow, Poland.ORCID https://orcid.org/0000-0002-7900-1094
Oliwia MasriDepartment of Physiology, Faculty of Medical Sciences, Zabrze, Medical University of Silesia, Katowice, Poland.
Łukasz MagrowskiDepartment of Physiology, Faculty of Medical Sciences, Zabrze, Medical University of Silesia, Katowice, Poland.
Wojciech KarczDepartment of General, Visceral, Transplantation and Vascular Surgery, Hospital of the Ludwig Maximilian University, Munich, Germany.ORCID https://orcid.org/0000-0002-4711-3630
Jerzy JochemDepartment of Physiology, Faculty of Medical Sciences, Zabrze, Medical University of Silesia, Katowice, Poland.ORCID https://orcid.org/0000-0001-7403-2177
Medical University of Silesia · PLJagiellonian University · PLLudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic surgery procedures are designed not only for sustained weight loss but also for achieving positive metabolic changes, including improved glucose tolerance and insulin sensitivity, along with an increase in energy expenditure. Based on recent findings, the present study focuses on the relationship between the effects of ileal transposition (IT), high-fat diet (HFD), and selected markers of lipid metabolism and inflammation.

methodsForty-eight male rats were divided into two groups: HFD and control diet (CD) fed rats. After eight weeks, animals in each group were randomly assigned to two types of surgery: IT and SHAM. Thereafter, fifty percent of the animals in the HFD and CD groups had their diets changed, while the remaining half maintained their presurgery diets. Eight weeks after surgery, plasma levels of ANGPTL8, PTX3, leptin, and adiponectin were assessed.

resultsThe IT group pre- and postoperatively maintained on the HFD showed higher ANGPTL8 level compared to SHAM operated animals (

conclusionsThis study indicates that the outcomes of metabolic surgery can be greatly modified by HFD. The effects of the IT procedure in this experiment are ambiguous and do not provide a clear answer as to whether or not they are beneficial.

Identifiers

PMID34035808
PMCPMC8118740
OpenAlexW3157273116

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.