ArticleRoyal Society open science2021
Shortcomings of human-in-the-loop optimization of an ankle-foot prosthesis emulator: a case series.
Article in Royal Society open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 51 citations in OpenAlex.
- Phase-Based Haptic Feedback for Improved Neural Control of a Robotic Prosthetic Ankle: A Preliminary Study.IEEE robotics and automation letters · 2026Article
- User preference in the personalized control of an ankle prosthesis: a case study.Journal of neuroengineering and rehabilitation · 2026Article
- Modeling the biomechanical features affecting the metabolic rate of walking with a powered ankle-foot prosthesis.Frontiers in robotics and AI · 2025Article
- A Clinical Tuning Framework for Continuous Kinematic and Impedance Control of a Powered Knee-Ankle Prosthesis.IEEE journal of translational engineering in health and medicine · 2025Article
- Human factors considerations of Interaction between wearers and intelligent lower-limb prostheses: a prospective discussion.Journal of neuroengineering and rehabilitation · 2024Review
- Review
- Walking Ankle Biomechanics of Individuals With Transtibial Amputations Using a Prescribed Prosthesis and a Portable Bionic Prosthesis Under Myoelectric Control.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024Article
- Design, Control, and Evaluation of a Robotic Ankle-Foot Prosthesis Emulator.IEEE transactions on medical robotics and bionics · 2023Article
- A Review of Current State-of-the-Art Control Methods for Lower-Limb Powered Prostheses.Annual reviews in control · 2023Article
- Using human-in-the-loop optimization for guiding manual prosthesis adjustments: a proof-of-concept study.Frontiers in robotics and AI · 2023Article
- Human-prosthesis cooperation: combining adaptive prosthesis control with visual feedback guided gait.Journal of neuroengineering and rehabilitation · 2022Article
- A robotic emulator for the systematic exploration of transtibial biarticular prosthesis designs.Journal of rehabilitation and assistive technologies engineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human-in-the-loop optimization allows for individualized device control based on measured human performance. This technique has been used to produce large reductions in energy expenditure during walking with exoskeletons but has not yet been applied to prosthetic devices. In this series of case studies, we applied human-in-the-loop optimization to the control of an active ankle-foot prosthesis used by participants with unilateral transtibial amputation. We optimized the parameters of five control architectures that captured aspects of successful exoskeletons and commercial prostheses, but none resulted in significantly lower metabolic rate than generic control. In one control architecture, we increased the exposure time per condition by a factor of five, but the optimized controller still resulted in higher metabolic rate. Finally, we optimized for self-reported comfort instead of metabolic rate, but the resulting controller was not preferred. There are several reasons why human-in-the-loop optimization may have failed for people with amputation. Control architecture is an unlikely cause given the variety of controllers tested. The lack of effect likely relates to changes in motor adaptation, learning, or objectives in people with amputation. Future work should investigate these potential causes to determine whether human-in-the-loop optimization for prostheses could be successful.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.