Evidence map›Paper›PMID 34038202›Full record

ArticleThe Journal of international medical research2021

Predictors of pregnancy after intrauterine insemination in women with polycystic ovary syndrome.

Hui-Juan Guan, Lin-Qing Pan, Hang Song, Huai-Yun Tang, Li-Sha Tang

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hui-Juan GuanClinical Centre of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, Jiangsu Province, China.
Lin-Qing PanClinical Centre of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, Jiangsu Province, China.
Hang SongClinical Centre of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, Jiangsu Province, China.
Huai-Yun TangClinical Centre of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, Jiangsu Province, China.
Li-Sha TangClinical Centre of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, Jiangsu Province, China.ORCID https://orcid.org/0000-0002-4668-9072
Lianyungang Maternal and Children’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of body mass index (BMI) in patients with polycystic ovary syndrome (PCOS) undergoing controlled ovarian stimulation (COS) with intrauterine insemination (IUI).

methodsThis retrospective study evaluated couples with PCOS undergoing COS and IUI. The relationship between cumulative IUI pregnancy outcomes and BMI, treatment cycles, treatment schemes, number of dominant follicles, endometrial thickness, infertility duration and type of infertility was analysed.

resultsThe study evaluated 831 IUI cycles in 451 couples with PCOS. Compared with normoweight women, overweight and obese women required more human menopausal gonadotropin (hMG) doses and more days of COS. Gestational diabetes mellitus occurred more frequently in the obese group than in the other BMI groups. The clinical pregnancy and live birth rates in the hMG, clomiphene citrate (CC) + hMG and letrozole (LE) + hMG groups were significantly higher than those in the CC and LE groups. The clinical pregnancy rate was higher in the secondary infertility group compared with the primary infertility group.

conclusionObese women might require more hMG doses and more days of COS to overcome the effects of weight. As BMI increases, the incidence of gestational diabetes might also increase. The number of cycles and type of infertility may have a predictive value for pregnancy outcomes.

Indexed as

Infertility, FemalePolycystic Ovary SyndromeFemaleFertility Agents, FemaleHumansInseminationOvulation InductionPregnancyPregnancy RateRetrospective StudiesFertility Agents, Femalebody mass indexinfertilityintrauterine inseminationPolycystic ovary syndromepregnancy

Identifiers

PMID34038202
PMCPMC8161844
OpenAlexW3164421063

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.